Evidence map›Paper›PMID 33194241›Full record

ReviewBiomedical engineering letters2020

Freeform 3D printing of soft matters: recent advances in technology for biomedical engineering.

Shengyang Chen, Wen See Tan, Muhammad Aidil Bin Juhari, Qian Shi, Xue Shirley Cheng, Wai Lee Chan, Juha Song

Abstract readReview
In one paragraph

Review in Biomedical engineering letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Omnidirectional 3D Printing of Anisotropic Nanofibrous Peptide Hydrogels.bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Bioprinting a Tri-layered Skin Analogue.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Embedded 3D Bioprinting for Engineering Miniaturized In Vitro Tumor Models.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shengyang ChenSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Wen See TanSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Muhammad Aidil Bin JuhariSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Qian ShiSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Xue Shirley ChengSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Wai Lee ChanSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798 Singapore.
Juha SongSchool of Chemical and Biological Engineering, Nanyang Technological University, Singapore, 639798 Singapore.ORCID 0000-0002-3503-680X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, an emerging three-dimensional (3D) printing technique named freeform 3D printing has revolutionized the biomedical engineering field by allowing soft matters with or without cells to be printed and solidified with high precision regardless of their poor self-supportability. The key to this freeform 3D printing technology is the supporting matrices that hold the printed soft ink materials during omnidirectional writing and solidification. This approach not only overcomes structural design restrictions of conventional layer-by-layer printing but also helps to realize 3D printing of low-viscosity or slow-curing materials. This article focuses on the recent developments in freeform 3D printing of soft matters such as hydrogels, cells, and silicone elastomers, for biomedical engineering. Herein, we classify the reported freeform 3D printing systems into positive, negative, and functional based on the fabrication process, and discuss the rheological requirements of the supporting matrix in accordance with the rheological behavior of counterpart inks, aiming to guide development and evaluation of new freeform printing systems. We also provide a brief overview of various material systems used as supporting matrices for freeform 3D printing systems and explore the potential applications of freeform 3D printing systems in different areas of biomedical engineering.

Indexed as

Additive manufacturingBiomedical engineeringFreeform 3D printingSoft mattersSupporting matrix

Identifiers

PMID33194241
PMCPMC7655899

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.