Evidence map›Paper›PMID 33194090›Full record

ReviewWorld journal of gastrointestinal surgery2020

Exosomal noncoding RNAs in cholangiocarcinoma: Laboratory noise or hope?

Konstantinos Laschos, Dimitra Ioanna Lampropoulou, Gerasimos Aravantinos, Maria Piperis, Dimitrios Filippou, George Theodoropoulos, Maria Gazouli

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastrointestinal surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Role of Exosomal Non-Coding RNAsMicroRNA (Shariqah, United Arab Emirates) · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. The Role of Exosomal Non-Coding RNAs in Colorectal Cancer Drug Resistance.International journal of molecular sciences · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Konstantinos LaschosSecond Department of Medical Oncology, General Oncology Hospital of Kifissia "Agioi Anargiroi", Athens 14564, Greece.
Dimitra Ioanna LampropoulouSecond Department of Medical Oncology, General Oncology Hospital of Kifissia "Agioi Anargiroi", Athens 14564, Greece.
Gerasimos AravantinosSecond Department of Medical Oncology, General Oncology Hospital of Kifissia "Agioi Anargiroi", Athens 14564, Greece.
Maria PiperisRadiation Therapy Department, Iatropolis, Athens 15231, Greece.
Dimitrios FilippouDepartment of Anatomy and Surgical Anatomy, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
George Theodoropoulos1 Propaedeutic University Surgery Clinic, Hippocratio General Hospital, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
Maria GazouliDepartment of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. mgazouli@med.uoa.gr.
Hospital Agioi Anargyroi · GRNational and Kapodistrian University of Athens · GRAcropolis Museum · GRHippocration General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, extracellular vesicles and particularly exosomes have gained a lot of research interest due to their unique roles in several biological processes. Noncoding RNAs (microRNAs, long noncoding RNAs and circular RNAs) represent a class of functional RNA with distinct regulatory roles in tumorigenesis and cancer progression. Cholangiocarcinoma is a rare but highly aggressive type of malignancy that is very challenging to diagnose, especially in early stages; surgical resection still represents the sole potentially curative treatment option. Hence, there is an urgent need for the discovery of novel diagnostic and prognostic biomarkers. Hereby, we provide a comprehensive review of the most recent discoveries that focus on exosomal noncoding RNAs in cholangio-carcinoma with the aim to identify new molecular players that could be used as biomarkers and therapeutic targets.

Indexed as

CholangiocarcinomaCircular RNAsExosomesExtracellular vesiclesLong noncoding RNAsMicroRNAsPiwi-interacting RNAs

Identifiers

PMID33194090
PMCPMC7642347
OpenAlexW3095518822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.