Evidence map›Paper›PMID 33194080›Full record

ArticleAmerican journal of translational research2020

Glycine attenuates cerebrovascular remodeling via glycine receptor alpha 2 and vascular endothelial growth factor receptor 2 after stroke.

Zheng Chen, Xiang Wang, Haikang Liao, Tao Sheng, Panhong Chen, Hongchang Zhou, Yongliang Pan, Weiqin Liu, Hua Yao

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Src dependency of the regulation of LTP by alternative splicing ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Zheng ChenSchools of Medicine, Huzhou University, Huzhou Central Hospital Huzhou, PR China.
Xiang WangDivision of Vascular Surgery, East Hospital, Tongji University School of Medicine Shanghai, 200120, PR China.
Haikang LiaoInstitute of Life Sciences and Institute of Neuroscience, Wenzhou University Wenzhou, PR China.
Tao ShengSchools of Medicine, Huzhou University, Huzhou Central Hospital Huzhou, PR China.
Panhong ChenSchools of Medicine, Huzhou University, Huzhou Central Hospital Huzhou, PR China.
Hongchang ZhouSchools of Medicine, Huzhou University, Huzhou Central Hospital Huzhou, PR China.
Yongliang PanSchools of Medicine, Huzhou University, Huzhou Central Hospital Huzhou, PR China.
Weiqin LiuThe Affiliated Ganzhou Hospital of Nanchang University Ganzhou, PR China.
Hua YaoGuangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University Guilin, PR China.
Huzhou University · CNHuzhou Central Hospital · CNWenzhou University · CNGanzhou People's Hospital · CNShanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a dual-acting neurotransmitter, glycine plays critical roles in cerebral ischemia by activating both glycine receptors (GlyRs) and N-methyl-D-aspartate acid receptors (NMDARs). However, the involvement of glycine receptor alpha 2 (GlyRa2) in cerebral ischemia has not been explored. The objective of this study was to determine the mechanism of action of GlyRa2 in cerebrovascular remodeling. After induction of rat tMCAO, levels of the

Indexed as

BBBGlyRa2neurovascularpSTAT3tMCAOVEGFR2

Identifiers

PMID33194080
PMCPMC7653569
OpenAlexW3104739596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.