Evidence map›Paper›PMID 33194017›Full record

ArticleAmerican journal of translational research2020

Porous fish collagen for cartilage tissue engineering.

Hao Li, Ru Chen, Zihao Jia, Cheng Wang, Yong Xu, Chengde Li, Huitang Xia, Depeng Meng

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  8. Prokaryotic Collagen-Like Proteins as Novel Biomaterials.Frontiers in bioengineering and biotechnology · 2022
    Review
  9. Review
  10. Review
  11. Biomaterial-Assisted Regenerative Medicine.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hao LiResearch Institute of Plastic Surgery, Department of Pharmacology, Weifang Medical University Weifang, Shandong, P. R. China.
Ru ChenDepartment of Breast Surgery, Hainan General Hospital, Hainan Medical University Hainan, P. R. China.
Zihao JiaResearch Institute of Plastic Surgery, Department of Pharmacology, Weifang Medical University Weifang, Shandong, P. R. China.
Cheng WangDepartment of Orthopedics, Changzheng Hospital, Second Military Medical University Shanghai, P. R. China.
Yong XuDepartment of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, P. R. China.
Chengde LiResearch Institute of Plastic Surgery, Department of Pharmacology, Weifang Medical University Weifang, Shandong, P. R. China.
Huitang XiaResearch Institute of Plastic Surgery, Department of Pharmacology, Weifang Medical University Weifang, Shandong, P. R. China.
Depeng MengDepartment of Orthopedics, Changzheng Hospital, Second Military Medical University Shanghai, P. R. China.
Second Military Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cartilage defects repair is still a challenge in clinical practice until now. Although many breakthroughs have been achieved in cartilage repair using tissue engineering technology, there are still no scaffolds available for large-scale clinical applications. Currently, fish collagen (FC) is a natural source that is considered as an alternative to mammal-derived collagen in engineering cartilage tissue due to its excellent biocompatibility, suitable biodegradability, lack of immunogenicity, rich sources, low cost and minimal risk of transmitting zoonoses, which implies great potential for use in cartilage regeneration. Herein, we successfully prepared three-dimensional porous FC scaffolds from three different concentrations of FC (0.5%, 1% and 2%) by freeze-drying technology. Our results indicated that increasing the FC concentration resulted in comparable levels of suitable biodegradability and good biocompatibility but lead to a concurrent decrease in pore size and porosity and a significant increase in water absorption capacity and mechanical properties; further, initial scaffold dimension was only sustained in the 2% FC concentration. Moreover, the

Indexed as

cartilage regenerationFish collagennatural biomaterialsporous scaffoldtissue engineering

Identifiers

PMID33194017
PMCPMC7653596
OpenAlexW3104517732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.