Evidence map›Paper›PMID 33193951›Full record

ArticleThe Pan African medical journal2020

Very severe COVID-19 in the critically ill in Tunisia.

Imen Ben Saida, Emna Ennouri, Rayane Nachi, Khaoula Meddeb, Jihene Mahmoud, Nesrine Thabet, Salma Jerbi, Mohamed Boussarsar

Open access · greenAbstract read
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Imen Ben SaidaMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Emna EnnouriMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Rayane NachiMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Khaoula MeddebMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Jihene MahmoudMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Nesrine ThabetMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Salma JerbiMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Mohamed BoussarsarMedical Intensive Care Unit, Farhat Hached University Hospital, Faculty of medicine, University of Sousse, 4000, Sousse, Tunisia.
Hôpital Farhat Hached · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSARS-CoV-2 is an emerging health threat outbreak. It may cause severe viral pneumonia with Acute Respiratory Distress Syndrome requiring critical care. Aim: to describe clinical features and outcomes of critically ill patients with SARS-CoV-2 infection.

methodsit was a retrospective study carried out in the medical ICU of Farhat Hached teaching hospital between March 11 and May 7, 2020. All consecutive patients with RT-PCR confirmed COVID-19 were included. Clinical characteristics and outcomes were collected by reviewing medical records.

resultsduring the study period, 10 critically ill patients with COVID-19 were enrolled. Mean age, 51.8±6.3 years; 8(80%), male. The most common comorbidities were; diabetes mellitus, 6(60%), obesity 2(20%), chronic kidney disease 2(20%) and hypertension 1(10%). Mean SAPS II, 23.2±1.8. The mean arterial oxygen partial pressure to fractional inspired oxygen ratio at admission was 136.2±79.7. Noninvasive mechanical ventilation was used in 4(40%) patients and 7(70%) received invasive mechanical ventilation. Tidal volume and PEEP were set respectively within the median [IQR] of, 5.7[5.6-6.3]ml/Kg and 10.7[6.5-11.7]cm H

conclusionthis study demonstrated a particular profile of COVID-19 in the critically ill as a severe presentation in aged males with comorbidities presenting with an ARDS-like and neurological impairment with poor prognosis. The only survivals seem to have benefited from noninvasive ventilatory support.

Indexed as

BetacoronavirusAntiviral AgentsCardiovascular DiseasesComorbidityCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentCritical IllnessDeliriumDiabetes MellitusFemaleHospital MortalityHospitals, TeachingHumansHydroxychloroquineMaleAntiviral AgentsHydroxychloroquineacute respiratory distress syndromeCOVID-19pneumoniaSARS-CoV-2

Identifiers

PMID33193951
PMCPMC7608765
OpenAlexW3047807010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.