Evidence map›Paper›PMID 33193723›Full record

ArticleFrontiers in genetics2020

Observation and Control of Gene Expression Noise: Barrier Crossing Analogies Between Drug Resistance and Metastasis.

Michael Tyler Guinn, Yiming Wan, Sarah Levovitz, Dongbo Yang, Marsha R Rosner, Gábor Balázsi

Abstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Journal of biosciences · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael Tyler GuinnBiomedical Engineering Department, Stony Brook University, Stony Brook, NY, United States.
Yiming WanBiomedical Engineering Department, Stony Brook University, Stony Brook, NY, United States.
Sarah LevovitzBiomedical Engineering Department, Stony Brook University, Stony Brook, NY, United States.
Dongbo YangBen May Department for Cancer Research, The University of Chicago, Chicago, IL, United States.
Marsha R RosnerBen May Department for Cancer Research, The University of Chicago, Chicago, IL, United States.
Gábor BalázsiBiomedical Engineering Department, Stony Brook University, Stony Brook, NY, United States.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
Dynamics and evolution of synthetic and natural gene regulatory networksR35GM122561 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI BALAZSI, GABOR · 2017 to 2025
$4.2M
Regulation of RKIP FunctionR01GM121735 · NIGMS · UNIVERSITY OF CHICAGO · PI ROSNER, MARSHA R · 2017 to 2020
$1.6M
NIGMS NIH HHS R01 GM121735NIGMS NIH HHS R35 GM122561NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancercontroldrug resistancemetastasisnoisenon-genetic heterogeneitysynthetic biology

Identifiers

PMID33193723
PMCPMC7662081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.