Evidence map›Paper›PMID 33193661›Full record

ArticleFrontiers in genetics2020

Analysis and Screening of Reproductive Long Non-coding RNAs Through Genome-Wide Analyses of Goat Endometrium During the Pre-attachment Phase.

Linjun Hong, Qun Hu, Xupeng Zang, Yanshe Xie, Chen Zhou, Xian Zou, Yaokun Li, Ming Deng, Yongqing Guo, Guangbin Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Comprehensive characterization of lncRNA NJournal of animal science and biotechnology · 2025
    Article
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  3. Article
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  8. LncRNAs in domesticated animals: from dog to livestock species.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  9. Comprehensive Analysis of Long Noncoding RNA Modified by mInternational journal of molecular sciences · 2022
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Linjun HongCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Qun HuCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Xupeng ZangCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Yanshe XieCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Chen ZhouCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Xian ZouCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Yaokun LiCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Ming DengCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Yongqing GuoCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Guangbin LiuCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Dewu LiuCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Key Laboratory of Guangdong Province · CNSouth China Agricultural University · CNGuangdong Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reproduction in goat is highly impeded by implantation failure. Of concern, the underlying mechanism leading to embryo implantation remains unclear. In this study, deep sequencing was employed through strand-specific Ribo-Zero RNA-Seq to characterize transcriptome changes in the endometrium during the maternal recognition of pregnancy. A total of 996 differential transcripts (115 lncRNAs and 881 mRNAs) existing between the pregnant and non-pregnant endometrium were revealed through bioinformatics analysis. The screening was performed on lncRNAs (XR_001918173.1, LNC_002760, and LNC_000599) and LNC_009053, to determine their potential role in regulating the synthesis of retinol and endometrium remolding through the proteasome pathway, respectively. The hypothesis of whether certain lncRNAs, namely, LNC_007223, LNC_005256, and LNC_010092 could play important roles in embryo implantation was tested. These novel findings are of paramount relevance to further elucidate the molecular mechanisms of embryo implantation and uncover new targets to improve goat reproduction.

Indexed as

endometriumgoatimplantationlncRNARNA-seq

Identifiers

PMID33193661
PMCPMC7649795
OpenAlexW3094372548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.