ReviewFrontiers in genetics2020
Gender Differences in Depression: Evidence From Genetics.
Review in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Does physical activity really improve anxiety and depression in overweight or obese children and adolescents? A systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- Prevalence of Sleep Disturbance in Patients With Cancer: A Systematic Review and Meta-Analysis.Clinical nursing research · 2022Pooled it
- Coronary Endothelial Dysfunction Is Associated With Major Depressive Disorder in Men With Chest Pain and Nonobstructive Coronary Artery Disease.Journal of the American Heart Association · 2026Article
- Mental health disorders among Sudanese medical students amid the 2023 conflict: prevalence, predictors, and implications.BMC psychiatry · 2026Article
- Characteristics of parks associated with depression in women only: a cross-sectional study of 329,363 adults.BMC medicine · 2026Article
- Prevalence and associated factors of depression among persons with Tuberculosis in Ghana: A cross-sectional study.SAGE open medicine · 2026Article
- Predicting depressive symptoms among Polish university students through sociodemographic and lifestyle factors.Scientific reports · 2025Article
- War, displacement, and mental health: striving for health equity among young refugees and IDPs in Sudan.BMC public health · 2025Article
- Parallel Pathways, Divergent Outcomes: Adipose Tissue-Neural Crosstalk in Depression and Obesity.Journal of clinical medicine · 2025Review
- Interaction of early life stress and NAD + /SIRT1 pathway genetic risk promotes depression.Translational psychiatry · 2025Article
- Study on depression-free life expectancy in the elderly population in China.BMC public health · 2025Article
- The role of the Wnt/BDNF pathway in maternal SCH-induced autism-like phenotypes in offspring rats: behavioral and molecular mechanisms.Translational psychiatry · 2025Article
- Relationship Between the Socio-Demographic Index and the Burden of Depressive Disorders in Asia (2010-2021): A Population Based Study.Health science reports · 2025Article
- Association of low vitamin BEuropean child & adolescent psychiatry · 2025Article
- The Role of miRNAs in the Differential Diagnosis of Alzheimer's Disease and Major Depression: A Bioinformatics-Based Approach.International journal of molecular sciences · 2025Article
- Peripheral MicroRNA Signatures in Adolescent Depression.Biological psychiatry global open science · 2025Article
- Gender as a sensor of nurses' depression, compassion fatigue and resilience.BMC psychiatry · 2025Article
- Gender differences in like-sex middle-aged twins: an extended network analysis of depressive symptoms, cognitive functions and leisure activities.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Article
- Association between sleep patterns and depression in older adults: a cross-sectional study using data from the National Health and Nutrition Examination Survey 2007-2014.BMC geriatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compared with men, female accounts for a larger proportion of patients with depression. Behavioral genetics researches find gender differences in genetic underpinnings of depression. We found that gender differences exist in heritability and the gene associated with depression after reviewing relevant research. Both genes and gene-environment interactions contribute to the risk of depression in a gender-specific manner. We detailed the relationships between serotonin transporter gene-linked promoter region (5-HTTLPR) and depression. However, the results of these studies are very different. We explored the reasons for the contradictory conclusions and provided some suggestions for future research on the gender differences in genetic underpinnings of depression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.