Evidence map›Paper›PMID 33193644›Full record

ArticleFrontiers in genetics2020

Inhibition of DNA Methylation in

Christina R Steadman, Shounak Banerjee, Yuliya A Kunde, Claire K Sanders, Babetta L Marrone, Scott N Twary

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christina R SteadmanLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Shounak BanerjeeLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Yuliya A KundeLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Claire K SandersLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Babetta L MarroneLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Scott N TwaryLos Alamos National Laboratory, Bioenergy and Biome Sciences, Los Alamos, NM, United States.
Los Alamos National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic organisms regulate the organization, structure, and accessibility of their genomes through chromatin remodeling that can be inherited as epigenetic modifications. These DNA and histone protein modifications are ultimately responsible for an organism's molecular adaptation to the environment, resulting in distinctive phenotypes. Epigenetic manipulation of algae holds yet untapped potential for the optimization of biofuel production and bioproduct formation; however, epigenetic machinery and modes-of-action have not been well characterized in algae. We sought to determine the extent to which the biofuel platform species

Indexed as

5-aza-2′-deoxycytidinealgaebisulfite sequencingDNA methylationepigeneticsfatty acid synthesislipid accumulation

Identifiers

PMID33193644
PMCPMC7593850
OpenAlexW3093047149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.