Evidence map›Paper›PMID 33193617›Full record

ArticleFrontiers in genetics2020

Integrating Genetic and Genomic Analyses of Combined Health Data Across Ecotypes to Improve Disease Resistance in Indigenous African Chickens.

Georgios Banos, Victoria Lindsay, Takele T Desta, Judy Bettridge, Enrique Sanchez-Molano, Adriana Vallejo-Trujillo, Oswald Matika, Tadelle Dessie, Paul Wigley, Robert M Christley and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Forward Genetics in Apicomplexa Biology: The Host Side of the Story.Frontiers in cellular and infection microbiology · 2022
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Georgios BanosThe Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Victoria LindsayRoyal Veterinary College, University of London, London, United Kingdom.
Takele T DestaSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Judy BettridgeInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Enrique Sanchez-MolanoThe Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Adriana Vallejo-TrujilloSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Oswald MatikaThe Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Tadelle DessieLiveGene - Centre for Tropical Livestock Genetics and Health, International Livestock Research Institute, Addis Ababa, Ethiopia.
Paul WigleyInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Robert M ChristleyInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Peter KaiserThe Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Olivier HanotteCentre for Tropical Livestock Genetics and Health, Edinburgh, United Kingdom.
Androniki PsifidiThe Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Roslin Institute · GBUniversity of Nottingham · GBUniversity of Edinburgh · GBUniversity of Liverpool · GBNatural Resources Institute · GBUniversity of London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H009051/1Biotechnology and Biological Sciences Research Council BB/H009159/1Biotechnology and Biological Sciences Research Council BB/H009396/1
6 · The paper itself

Abstract

Poultry play an important role in the agriculture of many African countries. The majority of chickens in sub-Saharan Africa are indigenous, raised in villages under semi-scavenging conditions. Vaccinations and biosecurity measures rarely apply, and infectious diseases remain a major cause of mortality and reduced productivity. Genomic selection for disease resistance offers a potentially sustainable solution but this requires sufficient numbers of individual birds with genomic and phenotypic data, which is often a challenge to collect in the small populations of indigenous chicken ecotypes. The use of information across-ecotypes presents an attractive possibility to increase the relevant numbers and the accuracy of genomic selection. In this study, we performed a joint analysis of two distinct Ethiopian indigenous chicken ecotypes to investigate the genomic architecture of important health and productivity traits and explore the feasibility of conducting genomic selection across-ecotype. Phenotypic traits considered were antibody response to Infectious Bursal Disease (IBDV), Marek's Disease (MDV), Fowl Cholera (PM) and Fowl Typhoid (SG), resistance to

Indexed as

antibody responsesbody weightEthiopiaGEBVGWASindigenous chickensinfectious diseasesWGS

Identifiers

PMID33193617
PMCPMC7581896
OpenAlexW3091902895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.