Evidence map›Paper›PMID 33193603›Full record

ArticleFrontiers in genetics2020

tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation.

Anahi Molla-Herman, Margarita T Angelova, Maud Ginestet, Clément Carré, Christophe Antoniewski, Jean-René Huynh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. The Expression Pattern of tRNA-Derived Small RNAs in AdultInternational journal of molecular sciences · 2023
    Article
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  6. Article
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  8. Article
  9. Article
  10. Review
  11. The Dynamic Network of RNP RNase P Subunits.International journal of molecular sciences · 2021
    Review
  12. Article
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Anahi Molla-HermanCollège de France, CIRB, CNRS Inserm UMR 7241, PSL Research University, Paris, France.
Margarita T AngelovaTransgenerational Epigenetics & Small RNA Biology, Sorbonne Université, CNRS, Laboratoire de Biologie du Développement - Institut de Biologie Paris Seine, Paris, France.
Maud GinestetCollège de France, CIRB, CNRS Inserm UMR 7241, PSL Research University, Paris, France.
Clément CarréTransgenerational Epigenetics & Small RNA Biology, Sorbonne Université, CNRS, Laboratoire de Biologie du Développement - Institut de Biologie Paris Seine, Paris, France.
Christophe AntoniewskiARTbio Bioinformatics Analysis Facility, Sorbonne Université, CNRS, Institut de Biologie Paris Seine, Paris, France.
Jean-René HuynhCollège de France, CIRB, CNRS Inserm UMR 7241, PSL Research University, Paris, France.
Centre National de la Recherche Scientifique · FRInserm · FRSorbonne Université · FRTransgene (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

tRNA fragments (tRFs) are a class of small non-coding RNAs (sncRNAs) derived from tRNAs. tRFs are highly abundant in many cell types including stem cells and cancer cells, and are found in all domains of life. Beyond translation control, tRFs have several functions ranging from transposon silencing to cell proliferation control. However, the analysis of tRFs presents specific challenges and their biogenesis is not well understood. They are very heterogeneous and highly modified by numerous post-transcriptional modifications. Here we describe a bioinformatic pipeline (tRFs-Galaxy) to study tRFs populations and shed light onto tRNA fragments biogenesis in

Indexed as

DrosophilaNm methylationoogenesisRNase PtRFstRNA

Identifiers

PMID33193603
PMCPMC7586317
OpenAlexW3091970126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.