Evidence map›Paper›PMID 33193363›Full record

ArticleFrontiers in immunology2020

Programmed Cell Death Ligand (PD-L)-1 Contributes to the Regulation of CD4

Rafael de Freitas E Silva, Rosa Isela Gálvez, Valéria Rego Alves Pereira, Maria Edileuza Felinto de Brito, Siew Ling Choy, Hannelore Lotter, Lidia Bosurgi, Thomas Jacobs

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Exhausted PD-1Frontiers in immunology · 2022
    Article
  9. Role of the PD-1/PD-L1 Pathway in ExperimentalFrontiers in immunology · 2022
    Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rafael de Freitas E SilvaProtozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Rosa Isela GálvezProtozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Valéria Rego Alves PereiraDepartment of Immunology, Aggeu Magalhães Institute-Oswaldo Cruz Foundation, Recife, Brazil.
Maria Edileuza Felinto de BritoDepartment of Immunology, Aggeu Magalhães Institute-Oswaldo Cruz Foundation, Recife, Brazil.
Siew Ling ChoyDepartment of Molecular Parasitology and Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Hannelore LotterDepartment of Molecular Parasitology and Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Lidia BosurgiProtozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Thomas JacobsProtozoa Immunology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Bernhard Nocht Institute for Tropical Medicine · DEFundação Oswaldo Cruz · BRUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous Leishmaniasis (CL) affects up to one million people every year and treatments are costly and toxic. The regulation of the host immune response is complex and the knowledge of how CD4

Indexed as

AdolescentAdultAnimalsB7-H1 AntigenCD4-Positive T-LymphocytesCytokinesFemaleHumansInflammationLeishmaniaLeishmaniasis, CutaneousLymph NodesMacrophagesMaleMiceMiddle AgedB7-H1 AntigenCytokinesProgrammed Cell Death 1 ReceptorCD4 T cellco-inhibitory receptorsleishmaniasisPD-1 (CD279)PD-L1 (B7-H1 CD274)

Identifiers

PMID33193363
PMCPMC7642203
OpenAlexW3093740595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.