Evidence map›Paper›PMID 33193358›Full record

ArticleFrontiers in immunology2020

Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source.

Nicholas J Hess, Payton N Lindner, Jessica Vazquez, Samuel Grindel, Amy W Hudson, Aleksandar K Stanic, Akihiro Ikeda, Peiman Hematti, Jenny E Gumperz

Open access · goldAbstract readComparative Study
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Humanized immune system animal models and their recent applications.Animal models and experimental medicine · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Circulating IRF8-expressing CD123Trends in immunology · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Humanized mouse models for immuno-oncology research.Nature reviews. Clinical oncology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nicholas J HessDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Payton N LindnerDepartment of Obstetrics and Gynecology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Jessica VazquezDepartment of Obstetrics and Gynecology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Samuel GrindelDepartment of Medical Genetics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Amy W HudsonDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.
Aleksandar K StanicDepartment of Obstetrics and Gynecology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Akihiro IkedaDepartment of Medical Genetics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Peiman HemattiDivision of Hematology/Oncology, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
Jenny E GumperzDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, United States.
University of Wisconsin–Madison · USMedical College of Wisconsin · US

Funding

RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
Mechanisms of iNKT cell anti-viral adjuvancyR01AI136500 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GUMPERZ, JENNY E. · 2018 to 2022
$1.9M
University of Wisconsin Transplant Reseach Training ProgramT32AI125231 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KAUFMAN, DIXON B · 2016 to 2020
$1.2M
Understanding the impact of human NKT cells on hematopoiesisR21AI116007 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GUMPERZ, JENNY E. · 2015 to 2016
$421k
NHLBI NIH HHS T32 HL007899NIAID NIH HHS R01 AI136500NIAID NIH HHS R21 AI116007NIAID NIH HHS T32 AI125231
6 · The paper itself

Abstract

NBSGW mice are highly immunodeficient and carry a hypomorphic mutation in the

Indexed as

Cell LineageCord Blood Stem Cell TransplantationHematopoietic Stem Cell TransplantationMutationAnimalsAntigens, CD34B-LymphocytesCells, CulturedCell SurvivalFemaleHematopoietic Stem Cell MobilizationHematopoietic Stem CellsHumansImmunocompromised HostIntegrin alpha6Leukocyte Common AntigensAntigens, CD34Integrin alpha6Kit protein, mouseLeukocyte Common AntigensProto-Oncogene Proteins c-kitbone marrowc-KIT mutationG-CSF mobilized peripheral bloodHPSCHSChuman immune system micehuman neutrophil engraftmentumbilical cord blood

Identifiers

PMID33193358
PMCPMC7604455
OpenAlexW3093317379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.