Evidence map›Paper›PMID 33193311›Full record

ArticleFrontiers in immunology2020

HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1 Allele and Haplotype Frequencies of 28,927 Saudi Stem Cell Donors Typed by Next-Generation Sequencing.

Dunia Jawdat, F Aytül Uyar, Ahmed Alaskar, Carlheinz R Müller, Ali Hajeer

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in pharmacology · 2024
    Article
  9. HLA Genetics for the Human Diseases.Advances in experimental medicine and biology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Prevalence of exposure to pharmacogenetic drugs by the Saudis treated at the health care centers of the Ministry of National Guard.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
  16. Distribution ofFrontiers in pharmacology · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dunia JawdatSaudi Stem Cells Donor Registry, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
F Aytül UyarDepartment of Physiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
Ahmed AlaskarDepartment of Oncology, King Abdulaziz Medical City - Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Carlheinz R MüllerZKRD Zentrales Knochenmarkspender-Register für die Bundesrepublik Deutschland, Ulm, Germany.
Ali HajeerDepartment of Pathology and Laboratory Medicine, King Abdulaziz Medical City - Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human leukocyte antigen (HLA) allele and haplotype frequency distribution varies widely between different ethnicities and geographical areas. Matching for HLA alleles is essential for successful related and unrelated stem cell transplantation. Among the Saudi population, data on HLA alleles and haplotypes are limited. A cross-sectional study was performed on 28,927 bone marrow donors. The most frequent HLA alleles were HLA-A

Indexed as

Gene FrequencyHaplotypesStem CellsTissue DonorsAdolescentAdultFemaleHLA-A AntigensHLA-B AntigensHLA-C AntigensHLA-DP beta-ChainsHLA-DQ beta-ChainsHLA-DRB1 ChainsHumansMaleMiddle AgedHLA-A AntigensHLA-B AntigensHLA-C AntigensHLA-DPB1 antigenHLA-DP beta-ChainsHLA-DQB1 antigenHLA-DQ beta-ChainsHLA-DRB1 Chainsbone marrow registryhaplotype frequenciespopulation geneticsSaudi Arabiaunrelated donors

Identifiers

PMID33193311
PMCPMC7643328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.