Evidence map›Paper›PMID 33193306›Full record

Trial reportFrontiers in immunology2020

The Antigen Presenting Potential of CD21

Marlene E Reincke, Kathryn J Payne, Ina Harder, Valentina Strohmeier, Reinhard E Voll, Klaus Warnatz, Baerbel Keller

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 45 citations in OpenAlex.

  1. Elevated CD21Journal of clinical immunology · 2022
    Trial
  2. Review
  3. Elevated IL-10 is Linked With the Expansion of T-betJournal of clinical immunology · 2026
    Article
  4. Article
  5. Human CD21Journal of human immunity · 2026
    Review
  6. Article
  7. CD21Frontiers in aging · 2026
    Article
  8. P75iScience · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Expansion of CD57Frontiers in immunology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. CD11cNeurology(R) neuroimmunology & neuroinflammation · 2024
    Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marlene E ReinckeDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Kathryn J PayneDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Ina HarderDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Valentina StrohmeierDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Reinhard E VollDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Klaus WarnatzDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Baerbel KellerDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
University Medical Center Freiburg · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human CD21

Indexed as

Antigen PresentationImmunologic MemoryAgedAutoimmune DiseasesB-LymphocytesCD4-Positive T-LymphocytesCytokinesFemaleGene Expression RegulationHumansMaleMiddle AgedReceptors, Complement 3dCytokinesReceptors, Complement 3dantigen-presenting cellsautoimmunityCD21low B cellsco-stimulationT cell

Identifiers

PMID33193306
PMCPMC7609862
OpenAlexW3094269242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.