Evidence map›Paper›PMID 33193300›Full record

Trial reportFrontiers in immunology2020

A Specific

Alexandra Gomes Dos Santos, Elieser Hitoshi Watanabe, Daiane Tomomi Ferreira, Jamille Oliveira, Érika Shimoda Nakanishi, Claudia Silva Oliveira, Edimar Bocchi, Cristina Terra Gallafrio Novaes, Fatima Cruz, Noemia Barbosa Carvalho and 6 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Chagas Disease: An Opportunistic Infection in AIDS.Current infectious disease reports · 2026
    Article
  2. Review
  3. Article
  4. Chagas disease in immunocompromised patients.Clinical microbiology reviews · 2024
    Review
  5. Article
  6. Article
  7. Observational
  8. Immune network · 2022
    Article
  9. Article
  10. Chagas Disease in People with HIV: A Narrative Review.Tropical medicine and infectious disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Alexandra Gomes Dos SantosDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Elieser Hitoshi WatanabeDepartment of Medicine, Divisions of Molecular Medicine and Nephrology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Daiane Tomomi FerreiraLaboratory of Immunology (LIM 48), Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Jamille OliveiraDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Érika Shimoda NakanishiLaboratory of Immunology (LIM 48), Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Claudia Silva OliveiraDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Edimar BocchiHeart Institute, Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Cristina Terra Gallafrio NovaesDivision of Infectious Diseases, Hospital das Clinicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Fatima CruzHeart Institute, Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Noemia Barbosa CarvalhoDivision of Infectious Diseases, Hospital das Clinicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Paula Keiko SatoLaboratory of Immunology (LIM 48), Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Edite Hatsumi Yamashiro-KanashiroLaboratory of Immunology (LIM 48), Hospital das Clínicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Alessandra PontilloDepartament of Immunology, Instituto de Ciências Biomédicas (ICB), University of São Paulo, São Paulo, Brazil.
Vera Lucia Teixeira de FreitasDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Luiz Fernando OnuchicDepartment of Medicine, Divisions of Molecular Medicine and Nephrology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Maria Aparecida Shikanai-YasudaDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chagas disease caused by Methods: Two hundred twenty-six patients and 90 control individuals were analyzed. Results: Our data revealed association between a cytokine gene polymorphism and parasitemia never previously reported. The Conclusions: Our data support a protective role of

Indexed as

Chagas DiseaseGenotypeInterleukin-17Interleukin-18Interleukin-1betaInterleukin-6ParasitemiaPolymorphism, GeneticAdultFemaleHumansMaleMiddle AgedTrypanosoma cruziIL17A protein, humanIL18 protein, humanIL1B protein, humanIL6 protein, humanInterleukin-17Interleukin-18Interleukin-1betaInterleukin-6cardiomyopathyChagas diseaseHIVIL17 A and IL18 polymorphismsIL1 BIL6T. cruzi parasitemia

Identifiers

PMID33193300
PMCPMC7642879
OpenAlexW3094449864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.