Evidence map›Paper›PMID 33193266›Full record

ReviewFrontiers in microbiology2020

Streptococcal Serine-Rich Repeat Proteins in Colonization and Disease.

Jia Mun Chan, Andrea Gori, Angela H Nobbs, Robert S Heyderman

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jia Mun ChanNIHR Mucosal Pathogens Research Unit, Division of Infection and Immunity, University College London, London, United Kingdom.
Andrea GoriNIHR Mucosal Pathogens Research Unit, Division of Infection and Immunity, University College London, London, United Kingdom.
Angela H NobbsBristol Dental School, University of Bristol, Bristol, United Kingdom.
Robert S HeydermanNIHR Mucosal Pathogens Research Unit, Division of Infection and Immunity, University College London, London, United Kingdom.
University College London · GBUniversity of Bristol · GB

Funding

British Heart Foundation PG/17/10/32829Medical Research Council MR/N023129/1
6 · The paper itself

Abstract

Glycosylation of proteins, previously thought to be absent in prokaryotes, is increasingly recognized as important for both bacterial colonization and pathogenesis. For mucosal pathobionts, glycoproteins that function as cell wall-associated adhesins facilitate interactions with mucosal surfaces, permitting persistent adherence, invasion of deeper tissues and transition to disease. This is exemplified by

Indexed as

bacterial glycoproteinscolonizationpathogenesisserine-rich repeat proteinsStreptococcus agalactiaeStreptococcus pneumoniae

Identifiers

PMID33193266
PMCPMC7661464
OpenAlexW3094872053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.