Evidence map›Paper›PMID 33193095›Full record

ArticleFrontiers in endocrinology2020

Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway.

Abdulhafiz Imam Aliagan, Ngonidzashe B Madungwe, Nathalie Tombo, Yansheng Feng, Jean C Bopassa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abdulhafiz Imam AliaganDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Ngonidzashe B MadungweDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Nathalie TomboDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Yansheng FengDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Jean C BopassaDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
The University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Degradation of Mitochondrial Inner Membrane Protein Disrupts the Structural Interaction between Mitofilin and Cyclophilin D and Determines the Extent of Ischemia/reperfusion injuryR01HL138093 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BOPASSA, JEAN CHRISOSTOME · 2017 to 2021
$1.9M
NCATS NIH HHS UL1 TR001120NCI NIH HHS P30 CA054174NHLBI NIH HHS R01 HL138093
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidative StressAnimalsHippo KinasesIntracellular Signaling Peptides and ProteinsMaleMitochondriaMyocytes, CardiacProtective AgentsProtein Serine-Threonine KinasesRatsRats, Sprague-DawleyReceptors, G-Protein-CoupledReperfusion InjurySerine-Threonine Kinase 3YAP-Signaling ProteinsGper1 protein, ratHippo KinasesIntracellular Signaling Peptides and ProteinsProtective AgentsProtein Serine-Threonine KinasesReceptors, G-Protein-CoupledSerine-Threonine Kinase 3Stk3 protein, ratYap1 protein, ratYAP-Signaling Proteinscell cycleG protein-coupled estrogen receptor 1 (GPER1)mitochondrial dynamicsmitochondrial functionmPTP openingMST1/YAP pathwayrat cardiomyoblasts

Identifiers

PMID33193095
PMCPMC7604496
OpenAlexW3092762367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.