ReviewFrontiers in neurology2020
Sex, Drugs, and TBI: The Role of Sex in Substance Abuse Related to Traumatic Brain Injuries.
Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Substance Use and Traumatic Brain Injury: Evidence from a Rural Trauma Center.International journal of environmental research and public health · 2026Observational
- Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior.Journal of neurotrauma · 2025Article
- Incidence and mortality related risk factors in patients with severe traumatic brain injury: A meta‑analysis.Experimental and therapeutic medicine · 2025Article
- Self-reported head trauma among Native Americans who inject methamphetamine: a cross-sectional study.Frontiers in public health · 2025Article
- Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations.The lancet. Healthy longevity · 2024Review
- Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior.bioRxiv : the preprint server for biology · 2024Article
- Patterns of Alcohol Use in Hispanic Individuals with TBI over the Ten Years Post-Injury: A Model Systems Study.Journal of personalized medicine · 2024Article
- Adolescent alcohol and cannabis use as risk factors for head trauma in the Northern Finland Birth Cohort study 1986.European journal of public health · 2023Article
- Sex-Specific and Traumatic Brain Injury Effects on Dopamine Receptor Expression in the Hippocampus.International journal of molecular sciences · 2023Article
- High Risk of Substance Use Disorder-Related Outcomes in Veterans Released from Correctional Facilities in Mid to Late Life.Journal of general internal medicine · 2023Article
- The role of the stress system in recovery after traumatic brain injury: A tribute to Bruce S. McEwen.Neurobiology of stress · 2022Article
- Intimate partner violence, substance use, and health comorbidities among women: A narrative review.Frontiers in psychology · 2022Review
- Ovarian Steroids Mediate Sex Differences in Alcohol Reward After Brain Injury in Mice.Frontiers in behavioral neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Traumatic brain injuries (TBI) are a significant public health problem costing billions of dollars in healthcare costs and lost productivity while simultaneously reducing the quality of life for both patients and caregivers. Substance abuse is closely interconnected with TBI, as intoxicated individuals are at a greater risk of suffering brain injuries, and TBI may serve as a risk factor for the subsequent development of substance use disorders. There are also prominent sex differences in the etiology, epidemiology, and consequences of TBI. For instance, men are more likely to be injured on sporting fields or in auto accidents, while women are disproportionately likely to suffer TBI associated with intimate partner violence. Moreover, while men are much more likely to suffer TBI during late adolescence-young adulthood, sex differences in the incidence of TBI are much less prominent during other developmental epochs. Further, there are prominent sex differences in substance abuse biology; for example, while more men meet diagnostic criteria for substance abuse disorders, women tend to advance from casual use to addiction more quickly. In this paper, we will discuss the emerging clinical and preclinical evidence that these sex differences in TBI and substance abuse interact and may be prominent determinates of long-term outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.