Evidence map›Paper›PMID 33192616›Full record

ArticleFrontiers in physiology2020

Hypercapnia-Driven Skeletal Muscle Dysfunction in an Animal Model of Pulmonary Emphysema Suggests a Complex Phenotype.

Joseph Balnis, Chun Geun Lee, Jack A Elias, Ariel Jaitovich

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Deaccelerated Myogenesis and Autophagy in Genetically Induced Pulmonary Emphysema.American journal of respiratory cell and molecular biology · 2022
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joseph BalnisDivision of Pulmonary and Critical Care Medicine, Albany Medical College, Albany, NY, United States.
Chun Geun LeeDepartment of Molecular Microbiology and Immunology, Brown University, Providence, RI, United States.
Jack A EliasDepartment of Molecular Microbiology and Immunology, Brown University, Providence, RI, United States.
Ariel JaitovichDivision of Pulmonary and Critical Care Medicine, Albany Medical College, Albany, NY, United States.
Albany Medical Center Hospital · USBrown University · US

Funding

Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J · 2013 to 2025
$24.9M
Chitinase1 as a Biomarker and Therapeutic Target in Scleroderma Lung DiseaseR01HL115813 · NHLBI · BROWN UNIVERSITY · PI LEE, CHUN GEUN · 2014 to 2017
$1.5M
Mechanisms and clinical relevance of hypercapnia-induced skeletal muscle atrophy in Chronic Obstructive Pulmonary Disease (COPD)K01HL130704 · NHLBI · ALBANY MEDICAL COLLEGE · PI JAITOVICH, ADOLFO ARIEL · 2016 to 2021
$835k
NHLBI NIH HHS K01 HL130704NHLBI NIH HHS P01 HL114501NHLBI NIH HHS R01 HL115813
6 · The paper itself

Abstract

Patients with chronic pulmonary conditions such as chronic obstructive pulmonary disease (COPD) often develop skeletal muscle dysfunction, which is strongly and independently associated with poor outcomes including higher mortality. Some of these patients also develop chronic CO

Indexed as

COPDhypercapniamuscle atrophymuscle dysfunctionpulmonary emphysema

Identifiers

PMID33192616
PMCPMC7658396
OpenAlexW3096797060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.