Evidence map›Paper›PMID 33192593›Full record

ArticleFrontiers in physiology2020

An

Intan Ruspita, Pragnya Das, Yan Xia, Sarah Kelangi, Keiko Miyoshi, Takafumi Noma, Malcolm L Snead, Rena N D'Souza, Marianna Bei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Annals of pediatrics & child health · 2025
    Article
  3. Enam expression is regulated by Msx2.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  4. Frontiers in physiology · 2023
    Article
  5. Article
  6. Article
  7. Sp6/Epiprofin is a master regulator in the developing tooth.Biochemical and biophysical research communications · 2021
    Article
  8. Article
  9. A Novel De NovoGenes · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 3 countries.

Intan RuspitaCenter for Regenerative and Developmental Biology, The Forsyth Institute, Cambridge, MA, United States.
Pragnya DasCenter for Regenerative and Developmental Biology, The Forsyth Institute, Cambridge, MA, United States.
Yan XiaCenter for Regenerative and Developmental Biology, The Forsyth Institute, Cambridge, MA, United States.
Sarah KelangiCenter for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Keiko MiyoshiDepartment of Molecular Biology, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Takafumi NomaFaculty of Human Life Studies, Hiroshima Jogakuin University, Hiroshima, Japan.
Malcolm L SneadCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry of USC, University of Southern California, Los Angeles, CA, United States.
Rena N D'SouzaUniversity of Utah, Salt Lake City, UT, United States.
Marianna BeiCenter for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Cooper University Hospital · USHarvard University · USHiroshima Jogakuin University · JPShriners Hospitals for Children - Boston · USTokushima University · JPUniversitas Gadjah Mada · IDUniversity of Southern California · USUniversity of Utah · US

Funding

New Molecules and Cures for Tooth AgenesisR01DE027255 · NIDCR · UNIVERSITY OF UTAH · PI JIA, SHIHAI · 2017 to 2020
$2.0M
Molecular and Genetic Pathways Controling Enamel FormationR21DE028091 · NIDCR · MASSACHUSETTS GENERAL HOSPITAL · PI BEI, MARIANNA · 2018 to 2019
$470k
NIDCR NIH HHS R01 DE027255NIDCR NIH HHS R21 DE028091
6 · The paper itself

Abstract

backgroundAmeloblasts are epithelially derived cells responsible for enamel formation through a process known as amelogenesis. Amongst the several transcription factors that are expressed during amelogenesis, both

methodsTwo different dental epithelial cell lines, the mouse LS8 and the rat G5 were used for either overexpression or silencing of

resultsUsing the above methods we identified that (i)

conclusionCollectively, these results show that

Indexed as

chromatin immunoprecipitationdental epithelial cellsfollistatinin situ hybridizationMsx2Sp6

Identifiers

PMID33192593
PMCPMC7649293
OpenAlexW3097433417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.