Evidence map›Paper›PMID 33192557›Full record

ArticleFrontiers in physiology2020

Effect of

Han-Bing Zhao, Lin Jia, Qing-Qing Yan, Qi Deng, Bo Wei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Recent advances in the positive role ofFrontiers in immunology · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Effect of dietaryFrontiers in immunology · 2025
    Article
  14. Sex-specific association between gutFrontiers in microbiology · 2025
    Article
  15. Virulence · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Han-Bing ZhaoDepartment of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Lin JiaDepartment of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Qing-Qing YanDepartment of Gastroenterology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, China.
Qi DengDepartment of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Bo WeiDepartment of Clinical Medicine, Guizhou Medical University, Guiyang, China.
Guangzhou First People's Hospital · CNGuangzhou Medical University · CNGuiyang Medical University · CNSouth China University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsSevere acute pancreatitis (SAP) is associated with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS), but treatment of these conditions is difficult. We studied a rat model of SAP + IAH to determine the effect of oral administration of

methodsA total of 48 rats were assigned to four groups, with 12 rats per group: Sham, SAP+IAH, SAP+IAH+

resultsInduction of SAP + IAH altered several functions of the intestinal barrier, and enhanced intestinal permeability, decreased the levels of ZO-1, claudin-1, occludin, the richness and diversity of the microflora community, the relative abundance (RA) of Firmicutes, and the number of probiotic organisms. However, induction of SAP+IAH increased the expression of claudin-2, MMP9, and TNF-α, and the RA of Proteobacteria and pathogens in the feces. Rats that received oral

conclusionThis study of rats with SAP+IAH indicated that oral dosing of

Indexed as

butyrateClostridium butyricumintestinal barrier functionintra-abdominal hypertensionsevere acute pancreatitis

Identifiers

PMID33192557
PMCPMC7658654
OpenAlexW3097891435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.