Evidence map›Paper›PMID 33192503›Full record

ReviewFrontiers in pharmacology2020

Systematic Review and Pharmacological Considerations for Chloroquine and Its Analogs in the Treatment for COVID-19.

Hongwei Peng, Zhangren Chen, Yunyun Wang, Simei Ren, Tiantian Xu, Xin Lai, Jinhua Wen, Mengjun Zhao, Chuanfei Zeng, Lijuan Du and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Modelling sudden cardiac death risks factors in patients with coronavirus disease of 2019: the hydroxychloroquine and azithromycin case.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Article
  3. COVID-19 and gastroenteric manifestations.World journal of clinical cases · 2021
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Hongwei PengDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhangren ChenDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yunyun WangAcademic Affairs Office, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Simei RenNational Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Chinese Academy of Medical Sciences, Beijing, China.
Tiantian XuDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xin LaiDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jinhua WenDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Mengjun ZhaoThe First Clinical Medical College of Nanchang University, Nanchang, China.
Chuanfei ZengThe First Clinical Medical College of Nanchang University, Nanchang, China.
Lijuan DuThe First Clinical Medical College of Nanchang University, Nanchang, China.
Yanmei ZhangThe First Clinical Medical College of Nanchang University, Nanchang, China.
Li CaoDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jinfang HuDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiaohua WeiDepartment of Pharmacy, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Tao HongDepartment of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNFirst Affiliated Hospital of Nanchang University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 has been announced pandemic by WHO and over 17,000,000 people infected (Till April 21st 2020). The disease is currently under control in China, with a curative rate of 86.8%. Chloroquine (CQ) is an old anti-malarial drug with good tolerability, which had proved to be effective in previous SARS-coronavirus, which spread and disappeared between 2002-2003. In vitro studies demonstrated the efficacy of CQ in curing COVID-19. Consequently,

Indexed as

chloroquineCOVID-19hydroxychloroquinepharmacological considerationspiperaquine

Identifiers

PMID33192503
PMCPMC7655531
OpenAlexW3097225318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.