Evidence map›Paper›PMID 33192479›Full record

ArticleFrontiers in aging neuroscience2020

Detection of Cerebrovascular Loss in the Normal Aging C57BL/6 Mouse Brain Using

Lindsay K Hill, Dung Minh Hoang, Luis A Chiriboga, Thomas Wisniewski, Martin J Sadowski, Youssef Z Wadghiri

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Novel intravital approaches to quantify deep vascular structure and perfusion in the aging mouse brain using ultrasound localization microscopy (ULM).Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Capillaries as a Therapeutic Target for Heart Failure.Journal of atherosclerosis and thrombosis · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lindsay K HillDepartment of Chemical and Biomolecular Engineering, NYU Tandon School of Engineering, Brooklyn, NY, United States.
Dung Minh HoangDepartment of Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), NYU Grossman School of Medicine, New York, NY, United States.
Luis A ChiribogaDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, United States.
Thomas WisniewskiDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, United States.
Martin J SadowskiDepartment of Neurology, NYU Grossman School of Medicine, New York, NY, United States.
Youssef Z WadghiriDepartment of Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), NYU Grossman School of Medicine, New York, NY, United States.
New York University · USAdvanced Imaging Research (United States) · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8M
Transgenic/Behavior CoreP01AG060882 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI UEBERHEIDE, BEATRIX MAGDALENA · 2020 to 2024
$12.0M
Targeting the apoE/A-beta Interaction as a Therapeutic Approach for ADR01AG031221 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SADOWSKI, MARTIN JOSEPH · 2008 to 2020
$4.0M
Mechanisms of Apolipoprotein E Isoform Conferred Susceptibility and Resistance to Alzheimer's DiseaseR01AG053990 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SADOWSKI, MARTIN JOSEPH · 2016 to 2020
$2.1M
7T Small Animal MRI Scanner Replacement for Translational Imaging ResourceS10OD018337 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BOADA, FERNANDO E · 2014 to 2014
$2.0M
Peptoid Antagonists of the ApoE/ABeta Interaction as a Novel Anti-ABeta Therapy.K02AG034176 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SADOWSKI, MARTIN JOSEPH · 2009 to 2014
$648k
Sandy Recovery Ventana Medical Systems Discovery XTS10OD018338 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHIRIBOGA, LUIS A · 2014 to 2014
$123k
NCATS NIH HHS UL1 TR000038NCI NIH HHS P30 CA016087NIA NIH HHS K02 AG034176NIA NIH HHS P01 AG060882NIA NIH HHS P30 AG066512NIA NIH HHS R01 AG031221NIA NIH HHS R01 AG053990NIBIB NIH HHS P41 EB017183NIH HHS S10 OD018337NIH HHS S10 OD018338
6 · The paper itself

Abstract

Microvascular rarefaction, or the decrease in vascular density, has been described in the cerebrovasculature of aging humans, rats, and, more recently, mice in the presence and absence of age-dependent diseases. Given the wide use of mice in modeling age-dependent human diseases of the cerebrovasculature, visualization, and quantification of the global murine cerebrovasculature is necessary for establishing the baseline changes that occur with aging. To provide

Indexed as

blood pool agentcerebral blood volume (CBV)magnetic resonance (MR) angiographymouse brain agingMRIrarefaction

Identifiers

PMID33192479
PMCPMC7606987
OpenAlexW3093873509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.