Evidence map›Paper›PMID 33192465›Full record

ArticleFrontiers in aging neuroscience2020

Compromised Behavior and Gamma Power During Working Memory in Cognitively Healthy Individuals With Abnormal CSF Amyloid/Tau.

Roger Rochart, Quanying Liu, Alfred N Fonteh, Michael G Harrington, Xianghong Arakaki

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Diagnostic utility of electrophysiological markers for early and differential diagnosis of Alzheimer's, Frontotemporal, and Lewy Body dementias: A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Behavioral Phenotype Associations With Resting State EEG Signal Complexity and Power Spectral Density in Fragile X Syndrome.Autism research : official journal of the International Society for Autism Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Roger RochartNeurosciences, Huntington Medical Research Institutes, Pasadena, CA, United States.
Quanying LiuDepartment of Biomedical Engineering, Southern University of Science and Technology (SUSTech), Shenzhen, China.
Alfred N FontehNeurosciences, Huntington Medical Research Institutes, Pasadena, CA, United States.
Michael G HarringtonNeurosciences, Huntington Medical Research Institutes, Pasadena, CA, United States.
Xianghong ArakakiNeurosciences, Huntington Medical Research Institutes, Pasadena, CA, United States.
Huntington Medical Research Institutes · USSouthern University of Science and Technology · CN

Funding

Cognitive challenge to reveal presymptomatic Alzheimer's diseaseR56AG063857 · NIA · HUNTINGTON MEDICAL RESEARCH INSTITUTES · PI ARAKAKI, XIANGHONG, HARRINGTON, MICHAEL GORDON · 2019 to 2019
$513k
NIA NIH HHS R56 AG063857
6 · The paper itself

Abstract

Research shows that gamma activity changes in Alzheimer's disease (AD), revealing synaptic pathology and potential therapeutic applications. We aim to explore whether cognitive challenge combined with quantitative EEG (qEEG) can unmask abnormal gamma frequency power in healthy individuals at high risk of developing AD. We analyzed low (30-50 Hz) and high gamma (50-80 Hz) power over six brain regions at EEG sensor level (frontal/central/parietal/left temporal/right temporal/occipital) in a dataset collected from an aging cohort during N-back working memory (WM) testing at two different load conditions (

Indexed as

behavioral performanceCH-NATCH-PATEEGgammahigh risk of Alzheimer’s diseaseworking memory

Identifiers

PMID33192465
PMCPMC7591805
OpenAlexW3093145614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.