Evidence map›Paper›PMID 33192425›Full record

ArticleFrontiers in human neuroscience2020

The Upper Extremity Flexion Synergy Is Minimally Expressed in Young Individuals With Unilateral Cerebral Palsy Following an Early Brain Injury.

Nayo M Hill, Julius P A Dewald

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Characterization of Atypical Corticospinal Tract Microstructure and Hand Impairments in Early-Onset Hemiplegic Cerebral Palsy: Preliminary Findings.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2023
    Article
  6. Article
  7. Heliyon · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nayo M HillDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, United States.
Julius P A DewaldDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, United States.
Northwestern University · US

Funding

The Loss of Independent Joint Control of the Upper Limb in Spastic Hemiparetic CPR01NS058667 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P · 2008 to 2022
$2.8M
Interdisciplinary Graduate Education in Movement and Rehabilitation Sciences-RenewalT32EB009406 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2009 to 2026
$2.2M
NIBIB NIH HHS T32 EB009406NINDS NIH HHS R01 NS058667
6 · The paper itself

Abstract

Hemiparetic stroke in adulthood often results in the grouped movement pattern of the upper extremity flexion synergy thought to arise from an increased reliance on cortico-reticulospinal pathways due to a loss of lateral corticospinal projections. It is well established that the flexion synergy induces reaching constraints in individuals with adult-onset hemiplegia. The expression of the flexion synergy in individuals with brain injuries onset earlier in the lifespan is currently unknown. An early unilateral brain injury occurring prior to six months post full-term may preserve corticospinal projections which can be used for independent joint control and thus minimizing the expression of the flexion synergy. This study uses kinematics of a ballistic reaching task to evaluate the expression of the flexion synergy in individuals with pediatric hemiplegia (PH) ages six to seventeen years. Fifteen individuals with brain injuries before birth (

Indexed as

cerebral palsyflexion synergyindependent joint controlpediatric hemiparesisperinatal strokereaching

Identifiers

PMID33192425
PMCPMC7596321
OpenAlexW3092670340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.