ArticleFrontiers in human neuroscience2020
Directional Local Field Potentials in the Subthalamic Nucleus During Deep Brain Implantation of Parkinson's Disease Patients.
Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Local field potential biomarkers for adaptive deep brain stimulation in Parkinson's disease: A scoping review.Surgical neurology international · 2026Review
- Subthalamic beta activity and neuroimaging concordance in deep brain stimulation: electrode placement and clinical outcomes.Clinical neurophysiology practice · 2026Article
- Online prediction of optimal deep brain stimulation contacts from local field potentials in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Spectral Topography of the Subthalamic Nucleus to Inform Next-Generation Deep Brain Stimulation.Movement disorders : official journal of the Movement Disorder Society · 2023Article
- Combining Multimodal Biomarkers to Guide Deep Brain Stimulation Programming in Parkinson Disease.Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- Review
- Surgical Strategy for Directional Deep Brain Stimulation.Neurologia medico-chirurgica · 2022Article
- Differential dopaminergic modulation of spontaneous cortico-subthalamic activity in Parkinson's disease.eLife · 2021Article
- Directional Local Field Potentials in the Subthalamic Nucleus During Deep Brain Implantation of Parkinson's Disease Patients.Frontiers in human neuroscience · 2020Article
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5 authors.
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Abstract
Segmented deep brain stimulation leads feature directional electrodes that allow for a finer spatial control of electrical stimulation compared to traditional ring-shaped electrodes. These segmented leads have demonstrated enlarged therapeutic windows and have thus the potential to improve the treatment of Parkinson's disease patients. Moreover, they provide a unique opportunity to record directional local field potentials. Here, we investigated whether directional local field potentials can help identify the best stimulation direction to assist device programming. Four Parkinson's disease patients underwent routine implantation of the subthalamic nucleus. Firstly, local field potentials were recorded in three directions for two conditions: In one condition, the patient was at rest; in the other condition, the patient's arm was moved. Secondly, current thresholds for therapeutic and side effects were identified intraoperatively for directional stimulation. Therapeutic windows were calculated from these two thresholds. Thirdly, the spectral power of the total beta band (13-35 Hz) and its sub-bands low, high, and peak beta were analyzed
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