Evidence map›Paper›PMID 33192283›Full record

ArticleFrontiers in neuroscience2020

Pigment Dispersing Factors and Their Cognate Receptors in a Crustacean Model, With New Insights Into Distinct Neurons and Their Functions.

Jodi L Alexander, Andrew Oliphant, David C Wilcockson, Timothy Brendler-Spaeth, Heinrich Dircksen, Simon G Webster

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Jodi L AlexanderSchool of Natural Sciences, Brambell Laboratories, Bangor University, Bangor, United Kingdom.
Andrew OliphantInstitute of Biological Environmental and Rural Sciences, Edward Llwyd Building, Aberystwyth University, Aberystwyth, United Kingdom.
David C WilcocksonInstitute of Biological Environmental and Rural Sciences, Edward Llwyd Building, Aberystwyth University, Aberystwyth, United Kingdom.
Timothy Brendler-SpaethInstitute of Biological Environmental and Rural Sciences, Edward Llwyd Building, Aberystwyth University, Aberystwyth, United Kingdom.
Heinrich DircksenDepartment of Zoology, Stockholm University, Stockholm, Sweden.
Simon G WebsterSchool of Natural Sciences, Brambell Laboratories, Bangor University, Bangor, United Kingdom.
Bangor University · GBInstitute of Biological, Environmental and Rural Sciences · GBAberystwyth University · GBStockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigment dispersing factors (PDFs, or PDHs in crustaceans) form a structurally related group of neuropeptides found throughout the Ecdysozoa and were first discovered as pigmentary effector hormones in crustaceans. In insects PDFs fulfill crucial neuromodulatory roles, most notably as output regulators of the circadian system, underscoring their central position in physiological and behavioral organization of arthropods. Intriguingly, decapod crustaceans express multiple isoforms of PDH originating from separate genes, yet their differential functions are still to be determined. Here, we functionally define two PDH receptors in the crab

Indexed as

functionsgene expressionG protein-coupled receptor deorphaningneuroanatomypigment dispersing hormone

Identifiers

PMID33192283
PMCPMC7658428
OpenAlexW3096686011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.