Evidence map›Paper›PMID 33192249›Full record

ArticleFrontiers in neuroscience2020

Human iPSC-Derived Neuronal Cells From

S Vijayalingam, Uthayashanker R Ezekiel, Fenglian Xu, T Subramanian, Elizabeth Geerling, Brittany Hoelscher, KayKay San, Aravinda Ganapathy, Kyle Pemberton, Eric Tycksen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Delineating theInternational journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Isogenic iPSC-derivedFrontiers in neuroscience · 2025
    Article
  5. Article
  6. A novelFrontiers in genetics · 2024
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

S VijayalingamDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
Uthayashanker R EzekielDepartment of Clinical Health Sciences, Doisy College of Health Science, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Fenglian XuDepartment of Biology and Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University, St. Louis, MO, United States.
T SubramanianDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
Elizabeth GeerlingDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
Brittany HoelscherDepartment of Biology and Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University, St. Louis, MO, United States.
KayKay SanDepartment of Clinical Health Sciences, Doisy College of Health Science, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Aravinda GanapathyDepartment of Clinical Health Sciences, Doisy College of Health Science, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Kyle PembertonDepartment of Biology and Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University, St. Louis, MO, United States.
Eric TycksenMcDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, United States.
Amelia K PintoDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
James D BrienDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
David B BeckNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.
Wendy K ChungDepartment of Pediatrics and Medicine, Columbia University Medical Center, New York, NY, United States.
Christina A GurnettDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
G ChinnaduraiDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Edward A. Doisy Research Center, St. Louis, MO, United States.
Saint Louis University · USColumbia University Irving Medical Center · USJames S. McDonnell Foundation · USNational Human Genome Research Institute · USWashington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
NCATS NIH HHS UL1 TR002345NICHD NIH HHS P50 HD103525NICHD NIH HHS U54 HD087011
6 · The paper itself

Abstract

A recurrent

Indexed as

CtBPde novo mutationintellectual and developmental disabilitiesinterferon responsetranscriptional repressiontranscriptome analysis

Identifiers

PMID33192249
PMCPMC7653094
OpenAlexW3094784904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.