Collagen Nanoparticle-Mediated Brain Silymarin Delivery: An Approach for Treating Cerebral Ischemia and Reperfusion-Induced Brain Injury.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

1. Therapeutic potential of flavonoids in neuroprotection: brain and spinal cord injury focus.Naunyn-Schmiedeberg's archives of pharmacology · 2025
   Pooled it
2. Hepatoprotective efficacy of silymarin-loaded metal-organic frameworks against CClPoultry science · 2026
   Article
3. Ancient and Emerging Nanostructures for Innovations to Fight Head and Neck Cancer.Cells · 2026
   Review
4. Cross-linked (R)-(+)-lipoic acid nanoparticles loaded with silibinin induce apoptosis and autophagy in glioblastoma cells.American journal of translational research · 2026
   Article
5. Biofabrication, statistical optimization, and characterization of collagen nanoparticles synthesized via Streptomyces cell-free system for cancer therapy.Scientific reports · 2025
   Article
6. A Synergistic Approach with Doxycycline and Spirulina Extracts in DNBS-Induced Colitis: Enhancing Remission and Controlling Relapse.Journal of xenobiotics · 2025
   Article
7. Pharmacological Potential ofCurrent issues in molecular biology · 2025
   Article
8. Noscapine-loaded collagen-based silver nanoparticles: a potent nano-therapeutic approach for cancer treatment.RSC advances · 2025
   Article
9. Green PEGylated-Sily@ZnFe2O4 nanocomposites for amelioration of ROS and DNA damage in rat liver.Scientific reports · 2025
   Article
10. Silibinin-loaded Nanostructured Lipid Carriers (NLCs) Ameliorated Lead-induced Acute Nephrotoxicity in Male Rats.Cell biochemistry and biophysics · 2024
    Article
11. Collagen and Its Derivatives Serving Biomedical Purposes: A Review.Polymers · 2024
    Review
12. Exploring Protein-Based Carriers in Drug Delivery: A Review.Pharmaceutics · 2024
    Review
13. Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection.International journal of molecular sciences · 2024
    Review
14. Current Trends in Gelatin-Based Drug Delivery Systems.Pharmaceutics · 2023
    Review
15. NLRP3 inflammasome activation increases brain oxidative stress after transient global cerebral ischemia in rats.The International journal of neuroscience · 2023
    Article
16. Ginsenoside Rb1 Improves Post-Cardiac Arrest Myocardial Stunning and Cerebral Outcomes by Regulating the Keap1/Nrf2 Pathway.International journal of molecular sciences · 2023
    Article
17. Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications.International journal of molecular sciences · 2023
    Review
18. Development of photoreactive demineralized bone matrix 3D printing colloidal inks for bone tissue engineering.Regenerative biomaterials · 2023
    Article
19. A systematic review of silymarin and silibinin mechanisms for attenuating cerebral ischemia-reperfusion injuries.Avicenna journal of phytomedicine
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

6 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as