Evidence map›Paper›PMID 33192118›Full record

ArticleJournal of ginseng research2020

Metabolomes and transcriptomes revealed the saponin distribution in root tissues of

Guangfei Wei, Feng Yang, Fugang Wei, Lianjuan Zhang, Ying Gao, Jun Qian, Zhongjian Chen, Zhengwei Jia, Yong Wang, He Su and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  3. A narrative review ofJournal of ginseng research · 2025
    Review
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  9. Horticulture research · 2024
    Review
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  11. Review
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  13. Article
  14. Article
  15. Article
  16. Frontiers in plant science · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Guangfei WeiKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Feng YangKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Fugang WeiWenshan Miaoxiang Notoginseng Technology, Co., Ltd., Wenshan, China.
Lianjuan ZhangKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ying GaoInstitute of Desertification Studies, Chinese Academy of Forestry, Beijing, China.
Jun QianKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Zhongjian ChenInstitute of Sanqi Research, Wenshan University, Wenshan, China.
Zhengwei JiaWaters Corporation Shanghai Science & Technology Co Ltd, Shanghai, China.
Yong WangInstitute of Sanqi Research, Wenshan University, Wenshan, China.
He SuKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Linlin DongKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Jiang XuKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Shilin ChenKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNWenshan University · CNInstitute of Desertification Studies · CNWaters (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsIn this study, the representative ginsenosides were detected and quantified by desorption electrospray ionization mass spectrometry and high-performance liquid chromatography analysis to demonstrate saponin distribution in the root tissues of

resultsThere was saponin distribution in the root tissues differed between

conclusionsThese results provided the visual and quantitative profiles of and confirmed the pivotal transcripts of CYPs and UGTs regulating the saponin distribution in the root tissues of

Indexed as

AACT, Acetoacetyl-CoA acyltransferaseDS, Dammarenediol-II synthaseDXPR, 1-deoxy-o-xylulose 5-phosphate reductoisomeraseDXPS, 1-deoxy-o-xylulose 5-phosphate synthaseFDR, False discovery rateFPP, Farnesyl diphosphateFPS, Farnesyl pyrophosphate synthaseGDPS, Gerenyl diphosphatesynthaseGO, Gene OntologyHDS, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphatesynthaseHMGR, 3-hydroxy-3-methylglutaryl-CoA reductaseHMGS, 3-hydroxy-3-methylglutaryl-CoA synthaseHPLC-UV, High-performance liquid chromatography-ultraviolet detectionIPPI, Isopentenyl pyrophosphate isomeraseIPP, Isoprenyl diphosphateISPD, 2-C-methylerythritol 4-phosphatecytidyl transferaseISPE, 4-(cytidine-5′-diphospho)-2-C-methylerythritol kinaseISPH, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductaseMALDI-MS, Matrix-assisted laser desorption/ionization–mass spectrometryMECPS, 2-C-methylerythritol-2,4-cyclophosphate synthaseMEP, 2-C-methyl-D-erythritol-4-phosphateMetabolomeMVA, Mevalonate acidMVD, Mevalonate diphosphate decarboxylaseMVK, Mevalonate kinaseNCBI Nr, NCBI Non-redundant proteinOPLS-DA, Orthogonal partial least squares-discriminant analysisORF, Open read frameP450, P450-monooxygenasePanax plantsPMK, Phosphomevalonate kinaseRoot tissuesSaponin distributionSE, Squalene epoxidaseSS, Squalene synthaseTranscriptomeUGTs, UDP-glycosyltransferasesUPLC-MS, Ultrahigh-performance liquid chromatography quadrupole time of flight-mass spectrometryWGCNA, Weighted gene coexpression network analysis

Identifiers

PMID33192118
PMCPMC7655499
OpenAlexW2947151528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.