ArticleJournal of pain research2020
Prediction of Postoperative Pain and Opioid Consumption Using Intraoperative Surgical Pleth Index After Surgical Incision: An Observational Study.
Article in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04724564 (Correlation of Different Time Measurements of the Surgical PLETH Index With Postoperative Pain; a Prospective Observational Study), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Correlation of Different Time Measurements of the Surgical PLETH Index With Postoperative Pain; a Prospective Observational Study
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review of Methods for Individual Prediction of Postoperative Pain.Pain research & management · 2025Pooled it
- Effect of transcutaneous electrical acupoint stimulation for preemptive analgesia on intraoperative opioid dosage in burn patients: a randomized, double-blind, controlled trial.Perioperative medicine (London, England) · 2026Article
- Predictive machine learning for postoperative pain using biosignals: a retrospective observational study.BMC medical informatics and decision making · 2025Observational
- Objective monitoring of acute pain and nociception in anaesthesia and intensive care: evidence and applications.Anaesthesiology intensive therapy · 2025Review
- Predictive value of surgical pleth index for early postoperative pain in children undergoing general anesthesia: a prospective observational study.BMC anesthesiology · 2025Observational
- Evaluating Anesthesia Guidance for Rescue Analgesia in Awake Patients Undergoing Carotid Endarterectomy with Cervical Plexus Blocks: Preliminary Findings from a Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Adequacy of Anesthesia Guidance for Combined General/Epidural Anesthesia in Patients Undergoing Open Abdominal Infrarenal Aortic Aneurysm Repair; Preliminary Report on Hemodynamic Stability and Pain Perception.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Possibility of Using Surgical Pleth Index in Predicting Postoperative Pain in Patients after Vitrectomy Performed under General Anesthesia.Diagnostics (Basel, Switzerland) · 2024Article
- Surgical pleth index monitoring in perioperative pain management: usefulness and limitations.Korean journal of anesthesiology · 2024Review
- Determining the optimum dose of remifentanil in combination with propofol for total intravenous anaesthesia in hysteroscopy under Narcotrend and SPI monitoring.Therapeutic advances in drug safety · 2024Article
- Adequacy of Anaesthesia for Nociception Detection during Vitreoretinal Surgery.Life (Basel, Switzerland) · 2023Article
- Predictive value of EEG-derived pain threshold index for acute postoperative pain in children.Frontiers in pediatrics · 2022Article
- An observational study to evaluate the utility of surgical plethysmographic index as a tool to predict postoperative pain in patients receiving oral calcium channel blocker therapy.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated whether the surgical pleth index (SPI) following surgical incision was related to postoperative pain and opioid consumption.
methodsThis prospective observational study was performed in 50 patients undergoing laparotomy under sevoflurane-based general anesthesia. We recorded the highest SPI during surgical incision. The postoperative pain with a numerical rating scale (NRS) and opioid consumption during postoperative 24 h were compared in patients who showed SPI over 50 (Group H) or 20-50 (Group L). The relationship between postoperative opioid consumption and SPI values (pre-incision, post-incision SPI value, change of SPI value, and post-incision SPI minus pre-incision SPI) was evaluated using receiver-operating characteristic analysis.
resultsThe mean of the highest SPI value during surgical incision was 56 (SD, 12; range, 26-85). Twenty-nine (63%) patients were included in Group H and 17 (37%) patients in Group L. There was a significant difference in NRS during recovery room stay and on postoperative 24 h in two groups (5 [5, 6] vs 7 [6, 8], p=0.007 and 3.5 [3, 5] vs 5 [5,6], p=0.006, Group L vs Group H). Group H used higher fentanyl via patient control analgesia during postoperative 24 h (573 (253) µg vs 817 (305) µg, p=0.008). A change of pre-incision and post-incision SPI value of 23, which showed the highest sensitivity (67%) and specificity (68%), was defined post hoc as the cut-off for fentanyl consumption during postoperative 24 h ≥1000 µg.
conclusionOur finding suggests that the SPI response to nociceptive stimuli during surgery is closely related to the degree of patient postoperative pain and opioid requirements. This information may be used to provide proper intraoperative analgesia and individual postoperative pain management.
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