Evidence map›Paper›PMID 33191957›Full record

ArticleTetrahedron2020

A convergent approach toward fidaxomicin: Syntheses of the fully glycosylated northern and southern fragments.

Ryan Hollibaugh, Xueliang Yu, Jef K De Brabander

Abstract read
In one paragraph

Article in Tetrahedron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ryan HollibaughDepartment of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9038, United States.
Xueliang YuDepartment of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9038, United States.
Jef K De BrabanderDepartment of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9038, United States.

Funding

Chemical and Biological Optimization of a Gram negative Selective AntibioticR01GM111329 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI DE BRABANDER, JEF KAREL · 2015 to 2016
$478k
NIGMS NIH HHS R01 GM111329
6 · The paper itself

Abstract

Efficient approaches that enable the synthesis of analogs of natural product antibiotics are needed to keep up with the emergence of multiply-resistant strains of pathogenic organisms. One promising candidate in this area is fidaxomicin, which boasts impressive

Indexed as

LipiarmycinMacrolide antibioticsRing closing metathesisTiacumicin

Identifiers

PMID33191957
PMCPMC7665079

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.