Evidence map›Paper›PMID 33191853›Full record

ArticleTissue engineering. Part A2021

Formation of Osteochondral Organoids from Murine Induced Pluripotent Stem Cells.

Shannon K O'Connor, Dakota B Katz, Sara J Oswald, Logan Groneck, Farshid Guilak

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 68 citations in OpenAlex.

  1. Bone organoids and mitochondrial reprogramming.Journal of orthopaedic translation · 2026
    Review
  2. Osteoarthritis as a systemic disease.Nature reviews. Rheumatology · 2026
    Review
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  4. Article
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  12. Revolutionizing bone healing: the role of 3D models.Cell regeneration (London, England) · 2025
    Review
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  18. Organoids in the oral and maxillofacial region: present and future.International journal of oral science · 2024
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shannon K O'ConnorDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Dakota B KatzDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Sara J OswaldDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Logan GroneckDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Farshid GuilakDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Shriners Hospitals for Children - St. Louis · USWashington University in St. Louis · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI Yousef Abu-Amer · 2019 to 2026
$6.8M
INTERDISCIPLINARY TRAINING IN MECHANOBIOLOGY FROM NM TO CMT32EB018266 · NIBIB · WASHINGTON UNIVERSITY · PI BAYLY, PHILIP V · 2014 to 2018
$987k
Functional Tissue Engineering of Cartilage Using Induced Pluripotent Stem CellsF31AR068217 · NIAMS · DUKE UNIVERSITY · PI O'CONNOR, SHANNON KATHLEEN · 2015 to 2016
$74k
NIAMS NIH HHS F31 AR068217NIAMS NIH HHS P30 AR074992NIBIB NIH HHS T32 EB018266NIGMS NIH HHS T32 GM007171
6 · The paper itself

Abstract

Osteoarthritis is a debilitating joint disease that is characterized by pathologic changes in both cartilage and bone, potentially involving cross talk between these tissues that is complicated by extraneous factors that are difficult to study

Indexed as

Induced Pluripotent Stem CellsOrganoidsAnimalsCell DifferentiationChondrogenesisHumansMiceOsteogenesisTissue ScaffoldschondrogeniciPSCorganoidosteoarthritisosteogenicscaffold-freetissue engineering

Identifiers

PMID33191853
PMCPMC8392116
OpenAlexW3102514336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.