Evidence map›Paper›PMID 33191702›Full record

ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2020

[Study on vascular remodeling, inflammatory response, and their correlations in acute spinal cord injury in rats].

Zixing Xu, Weihong Xu, Xuemin Chen, Yinan Zhou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zixing XuDepartment of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou Fujian, 350005, P.R.China.
Weihong XuDepartment of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou Fujian, 350005, P.R.China.
Xuemin ChenDepartment of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou Fujian, 350005, P.R.China.
Yinan ZhouDepartment of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou Fujian, 350005, P.R.China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the local vascular remodeling, inflammatory response, and their correlations following acute spinal cord injury (SCI) with different grades, and to assess the histological changes in SCI rats.

methodsOne hundred and sixteen adult female Sprague Dawley rats were randomly divided into 4 groups (

resultsDIF staining revealed that the ratio of RECA1 positive area was the highest in moderate group, higher in mild and severe groups, and the lowest in sham group with significant differences between groups (

conclusionIn the acute stage following mild or moderate SCI, progressively aggravated injury result in higher microvessel density and increased inflammation. However, at the SCI region, the relation between microvessel density and inflammation inverse with time in the different grades of SCI. Accordingly, the destruction of neural structures positively relate to the grades of SCI and severity of inflammation.

Indexed as

Spinal Cord InjuriesVascular RemodelingAnimalsFemaleRatsRats, Sprague-DawleySpinal CordTumor Necrosis Factor-alphaTumor Necrosis Factor-alphaangiogenesiscorrelation analysisinflammatory responseratSpinal cord injuryvascular remodeling

Identifiers

PMID33191702
PMCPMC8171710
OpenAlexW3106034262

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.