Evidence map›Paper›PMID 33191686›Full record

ArticleJournal of biomedical optics2020

Design and implementation of a portable colposcope Mueller matrix polarimeter.

Mariacarla Gonzalez, Karla Alejandra Montejo, Karl Krupp, Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan, Jessica C Ramella-Roman

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  5. Review
  6. Biomedical optics express · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mariacarla GonzalezFlorida International University, Biomedical Engineering Department, Miami, Florida, United States.
Karla Alejandra MontejoFlorida International University, Biomedical Engineering Department, Miami, Florida, United States.
Karl KruppPublic Health Research Institute of India, Mysore, Karnataka, India.
Vijaya SrinivasPublic Health Research Institute of India, Mysore, Karnataka, India.
Edward DeHoogOptical Engineering and Analysis, Long Beach, California, United States.
Purnima MadhivananPublic Health Research Institute of India, Mysore, Karnataka, India.
Jessica C Ramella-RomanFlorida International University, Biomedical Engineering Department, Miami, Florida, United States.
Florida International University · USPublic Health Research Institute Of India · INCalifornia State University, Long Beach · USUniversity of Arizona · US

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Longitudinal Study of Vaginal Microbiota and Persistent Human Papillomavirus DetectionR15AI128714 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI MADHIVANAN, PURNIMA · 2017 to 2017
$440k
FIC NIH HHS D43 TW010540NIAID NIH HHS R15 AI128714
6 · The paper itself

Abstract

significanceMueller matrix polarimetry can provide useful information about the function and structure of the extracellular matrix. A portable and low-cost system could facilitate the clinical assessment of cervical anomalies in low-resource settings.

aimWe introduce a low-cost snapshot Mueller matrix polarimeter that does not require external power, has no moving parts, and can acquire a full Mueller matrix in ∼1  s, to conduct a feasibility study for cervical imaging in the low-resource setting. APPROACH: A snapshot system based on two sets of Savart plates, a ring illuminator with polarizing elements (generating four polarization states), and one camera is introduced. Stokes vectors are formulated to recover the polarization properties of the sample. Then, using Mueller matrix decomposition, the depolarization and retardance information is extracted.

resultsWe report the results on 16 healthy individuals (out of 22 patients imaged), whose Pap smear showed no malignant findings from mobile clinics in rural region of Mysore, India. The depolarization and retardance information was in agreement with previous reports.

conclusionsWe introduce an imaging system and conducted a feasibility study on healthy individuals. This work could futurely translate into diagnostic applications to provide a quantitative platform in the clinical environment (e.g., cervical cancer screening).

Indexed as

ColposcopesUterine Cervical NeoplasmsDiagnostic ImagingEarly Detection of CancerFemaleHumansSpectrum AnalysiscollagencolposcopyMueller matrixpolarimetry

Identifiers

PMID33191686
PMCPMC7666868
OpenAlexW3105482064

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.