ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2020
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The safety of colorectal cancer surgery during the COVID-19: a systematic review and meta-analysis.Frontiers in oncology · 2023Pooled it
- Case fatality rate of the adult in-patients with COVID-19 and digestive system tumors: A systematic review and meta-analysis.Medicine · 2022Pooled it
- Mortality in adult patients with solid or hematological malignancies and SARS-CoV-2 infection with a specific focus on lung and breast cancers: A systematic review and meta-analysis.Critical reviews in oncology/hematology · 2021Pooled it
- Colorectal Cancer Surgery at a Regional Cold Site Centre During the SARS-CoV-2 Pandemic: A Comparison With Prepandemic Practices.Journal of surgical oncology · 2025Article
- Digestive and breast cancer patients managed during the first wave of COVID-19 pandemic: Short and middle term outcomes.World journal of methodology · 2024Article
- Impact of COVID-19 infection during the postoperative period in patients who underwent gastrointestinal surgery: a retrospective study.Annals of surgical treatment and research · 2024Article
- Impact of COVID-19 pandemic on short-term outcomes after low anterior resection in patients with rectal cancer: Analysis of data from the Japanese National Clinical Database.Annals of gastroenterological surgery · 2024Article
- Impact of COVID-19 Pandemic on the Clinical and Pathologic Characteristics of Colorectal Cancer: A Retrospective Multicenter Study in South Korea.Cancer management and research · 2024Article
- Impact of the COVID-19 Pandemic on Elective and Emergency Surgeries, and Postoperative Mortality in a Brazilian Metropolitan Area: A Time-Series Cohort Study.Risk management and healthcare policy · 2024Article
- Establishing a COVID-secure site for elective surgery during the COVID pandemic: An observational study.Journal of perioperative practice · 2023Observational
- Changes in Urologic Cancer Surgical Volume and Length of Stay During the COVID-19 Pandemic in Pennsylvania.JAMA network open · 2023Article
- Achieving a Textbook Outcome in Colon Cancer Surgery Is Associated with Improved Long-Term Survival.Current oncology (Toronto, Ont.) · 2023Article
- Has the COVID-19 pandemic changed the clinical picture and tumour stage at the time of presentation of patients with colorectal cancer? A retrospective cohort study.Cirugia espanola · 2023Article
- Has the COVID-19 pandemic changed the clinical picture and tumour stage at the time of presentation of patients with colorectal cancer? A retrospective cohort study.Cirugia espanola · 2023Article
- How SARS-CoV-2 Infection Impacts the Management of Patients with Vulvar Cancer: Experience in a Third-Level Hospital of Southern Italy.Journal of personalized medicine · 2023Article
- Impact of the COVID-19 pandemic on surgical care in the Netherlands.The British journal of surgery · 2022Article
- The Challenges of Colorectal Cancer Surgery during the COVID-19 Pandemic in Romania: A Three-Year Retrospective Study.International journal of environmental research and public health · 2022Article
- Impact of the COVID-19 Pandemic on the Elective Surgery for Colorectal Cancer: Lessons to Be Learned.Medicina (Kaunas, Lithuania) · 2022Review
- Colorectal cancer in patients with SARS-CoV-2: a systematic review and meta-analysis.Infectious agents and cancer · 2022Article
- Evaluating potential delays and outcomes of patients undergoing surgical resection for locally advanced and recurrent colorectal cancer during a pandemic.Annals of the Royal College of Surgeons of England · 2022Article
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Abstract
aimThis study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic.
methodThis was an international cohort study of patients undergoing elective resection of colon or rectal cancer without preoperative suspicion of SARS-CoV-2. Centres entered data from their first recorded case of COVID-19 until 19 April 2020. The primary outcome was 30-day mortality. Secondary outcomes included anastomotic leak, postoperative SARS-CoV-2 and a comparison with prepandemic European Society of Coloproctology cohort data.
resultsFrom 2073 patients in 40 countries, 1.3% (27/2073) had a defunctioning stoma and 3.0% (63/2073) had an end stoma instead of an anastomosis only. Thirty-day mortality was 1.8% (38/2073), the incidence of postoperative SARS-CoV-2 was 3.8% (78/2073) and the anastomotic leak rate was 4.9% (86/1738). Mortality was lowest in patients without a leak or SARS-CoV-2 (14/1601, 0.9%) and highest in patients with both a leak and SARS-CoV-2 (5/13, 38.5%). Mortality was independently associated with anastomotic leak (adjusted odds ratio 6.01, 95% confidence interval 2.58-14.06), postoperative SARS-CoV-2 (16.90, 7.86-36.38), male sex (2.46, 1.01-5.93), age >70 years (2.87, 1.32-6.20) and advanced cancer stage (3.43, 1.16-10.21). Compared with prepandemic data, there were fewer anastomotic leaks (4.9% versus 7.7%) and an overall shorter length of stay (6 versus 7 days) but higher mortality (1.7% versus 1.1%).
conclusionSurgeons need to further mitigate against both SARS-CoV-2 and anastomotic leak when offering surgery during current and future COVID-19 waves based on patient, operative and organizational risks.
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