Evidence map›Paper›PMID 33191456›Full record

ArticleCell and tissue research2020

Nephrocytes are part of the spectrum of filtration epithelial diversity.

Takayuki Miyaki, Yuto Kawasaki, Akira Matsumoto, Soichiro Kakuta, Tatsuo Sakai, Koichiro Ichimura

Open access · hybridAbstract read
In one paragraph

Article in Cell and tissue research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Anaesthesia of decapod crustaceans.Veterinary and animal science · 2022
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Takayuki MiyakiDepartment of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yuto KawasakiDepartment of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Akira MatsumotoDepartment of Biology, Juntendo University School of Medicine, Inzai, Chiba, Japan.
Soichiro KakutaLaboratory of Morphology and Image Analysis, Center for Biomedical Research Resources, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tatsuo SakaiDepartment of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Koichiro IchimuraDepartment of Anatomy and Life Structure, Juntendo University Graduate School of Medicine, Tokyo, Japan. ichimura@juntendo.ac.jp.ORCID http://orcid.org/0000-0001-6590-7912
Juntendo University · JP

Funding

Japan Society for the Promotion of Science JP15K18960Japan Society for the Promotion of Science JP17K08521
6 · The paper itself

Abstract

The excretory system produces urine by ultrafiltration via a filtration epithelium. Podocytes are widely found as filtration epithelial cells in eucoelomates. In some animal taxa, including insects and crustaceans, nephrocytes serve to separate toxic substances from the body fluid, in addition to podocytes. Drosophila nephrocytes have been recently utilized as a model system to study podocyte function and disease. However, functionality and cellular architecture are strikingly different between Drosophila nephrocytes and eucoelomate podocytes, and the phylogenetic relationship between these cells remains enigmatic. In this study, using focused-ion beam-scanning electron microscopy (FIB-SEM) tomography, we revealed three-dimensional architecture of decapod nephrocytes with unprecedented accuracy-they filled an enormous gap, which can be called "missing link," in the evolutionary diversity of podocytes and nephrocytes. Thus, we concluded that nephrocytes are part of the spectrum of filtration epithelial diversity in animal phylogeny.

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsPhylogenyPodocytesDrosophila Proteins3D ultrastructureDecapodFIB-SEM tomographyNephrocytesPodocytes

Identifiers

PMID33191456
PMCPMC7683493
OpenAlexW3102561452

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.