Evidence map›Paper›PMID 33191430›Full record

ArticleCardiovascular journal of Africa

Vascular health assessment with flow-mediated dilatation and retinal image analysis: a pilot study in an adult population from Cape Town.

Clara Marincowitz, Ingrid Webster, Corli Westcott, Nandu Goswami, Patrick de Boever, Gerald Seidel, Hans Strijdom

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Clara MarincowitzCentre for Cardio-metabolic Research in Africa, Division of Medical Physiology, Stellenbosch University, Cape Town, South Africa.
Ingrid WebsterCentre for Cardio-metabolic Research in Africa, Division of Medical Physiology, Stellenbosch University, Cape Town, South Africa. Email: iwebster@sun.ac.za.
Corli WestcottCentre for Cardio-metabolic Research in Africa, Division of Medical Physiology, Stellenbosch University, Cape Town, South Africa.
Nandu GoswamiDepartment of Physiology and Otto Loewi Research Centre, Medical University of Graz, Austria.
Patrick de BoeverHealth Unit, Flemish Institute for Technological Research (VITO), Mol; Centre for Environmental Sciences, Hasselt University, Diepenbeek; Department of Biology, University of Antwerp, Wilrijk, Belgium.
Gerald SeidelDepartment of Ophthalmology, Medical University of Graz, Austria.
Hans StrijdomCentre for Cardio-metabolic Research in Africa, Division of Medical Physiology, Stellenbosch University, Cape Town, South Africa.
Medical University of Graz · ATUniversity of Antwerp · BEFlemish Institute for Technological Research · BEHasselt University · BEStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFlow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors.

methodsEndothelial function (measured with FMD), microvascular structure (evaluated via fundus image analysis) and major CVD risk factors were assessed in 66 participants from Cape Town.

resultsMedian FMD% was 9.6%, with higher values in females. Mean retinal arteriolar and venular widths were

conclusionsWe report novel baseline FMD data in healthy South African adults from the Western Cape, and show that retinal microvascular calibres are associated with blood pressure. Our baseline FMD and RVA data could serve as a reference for future studies in South Africa.

Indexed as

Cardiovascular DiseasesHeart Disease Risk FactorsAdultDilatationFemaleHumansMaleMiddle AgedPilot ProjectsRetinaRisk FactorsSouth AfricaVenulescardiovascular riskendothelial functionflow‐mediated dilatationretinal imagingvascular health

Identifiers

PMID33191430
PMCPMC8756012
OpenAlexW3103677125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.