Evidence map›Paper›PMID 33191324›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Complete Resolution of a Case of TAFRO Syndrome Accompanied by Mediastinal Panniculitis, Adrenal Lesion, and Liver Damage with Hyperbilirubinemia.

Shiro Ono, Kiyomi Yoshimoto, Nobushiro Nishimura, Ryo Yoneima, Hiromasa Kawashima, Tadanao Kobayashi, Yoshiaki Tai, Makiko Miyamoto, Emiko Tsushima, Noritaka Yada and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Shiro OnoDepartment of General Medicine, Nara Medical University, Japan.
Kiyomi YoshimotoDepartment of General Medicine, Nara Medical University, Japan.
Nobushiro NishimuraDepartment of General Medicine, Nara Medical University, Japan.
Ryo YoneimaDepartment of General Medicine, Nara Medical University, Japan.
Hiromasa KawashimaDepartment of General Medicine, Nara Medical University, Japan.
Tadanao KobayashiDepartment of General Medicine, Nara Medical University, Japan.
Yoshiaki TaiDepartment of General Medicine, Nara Medical University, Japan.
Makiko MiyamotoDepartment of General Medicine, Nara Medical University, Japan.
Emiko TsushimaDepartment of General Medicine, Nara Medical University, Japan.
Noritaka YadaDepartment of General Medicine, Nara Medical University, Japan.
Kenji NishioDepartment of General Medicine, Nara Medical University, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TAFRO syndrome is a systemic inflammatory, lymphoproliferative disorder, but the pathophysiology of the disease is unknown. It is typically characterized by thrombocytopenia, anasarca, a fever, reticulin fibrosis, renal dysfunction, and organomegaly. However, other manifestations have been also reported. We encountered a 43-year-old man with TAFRO syndrome who showed mediastinal panniculitis, liver damage, and adrenal lesions in addition to the core signs. He achieved complete remission with combination therapy of corticosteroids, tocilizumab, and cyclosporin, and remission was maintained even after drug discontinuation at 15 months. Atypical manifestations and complete remission of TAFRO syndrome were remarkable features of our case.

Indexed as

Castleman DiseasePanniculitisAdultEdemaHumansHyperbilirubinemiaLiverMaleadrenal lesioncomplete resolutioncyclosporinliver damageTAFRO syndrometocilizumab

Identifiers

PMID33191324
PMCPMC8112990
OpenAlexW3101327890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.