Evidence map›Paper›PMID 33191288›Full record

ArticleThe Journal of rheumatology2021

Hospitalization Rates Are Highest in the First 5 Years of Systemic Sclerosis: Results From a Population-based Cohort (1980-2016).

Caitrin M Coffey, Avneek S Sandhu, Cynthia S Crowson, Sara J Achenbach, Eric L Matteson, Thomas G Osborn, Kenneth J Warrington, Ashima Makol

Abstract read
In one paragraph

Article in The Journal of rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caitrin M CoffeyC.M. Coffey, MD, Instructor of Medicine, T.G. Osborn, MD, Professor of Medicine, K.J. Warrington, MD, Professor of Medicine, A. Makol, MD, Assistant Professor of Medicine, Divison of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.ORCID 0000-0002-5170-4038
Avneek S SandhuA.S. Sandhu, MD, Resident Physician, Department of Internal Medicine, Kettering Medical Center, Kettering, Ohio.
Cynthia S CrowsonC.S. Crowson, PhD, Professor of Biostatistics and Medicine, E.L. Matteson, MD, Professor of Medicine, Divison of Rheumatology, and Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.ORCID 0000-0001-5847-7475
Sara J AchenbachS.J. Achenbach, MS, Stat Program Analyst II, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Eric L MattesonC.S. Crowson, PhD, Professor of Biostatistics and Medicine, E.L. Matteson, MD, Professor of Medicine, Divison of Rheumatology, and Department of Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.ORCID 0000-0002-9866-0124
Thomas G OsbornC.M. Coffey, MD, Instructor of Medicine, T.G. Osborn, MD, Professor of Medicine, K.J. Warrington, MD, Professor of Medicine, A. Makol, MD, Assistant Professor of Medicine, Divison of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.ORCID 0000-0001-5683-7895
Kenneth J WarringtonC.M. Coffey, MD, Instructor of Medicine, T.G. Osborn, MD, Professor of Medicine, K.J. Warrington, MD, Professor of Medicine, A. Makol, MD, Assistant Professor of Medicine, Divison of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.ORCID 0000-0002-2562-5133
Ashima MakolC.M. Coffey, MD, Instructor of Medicine, T.G. Osborn, MD, Professor of Medicine, K.J. Warrington, MD, Professor of Medicine, A. Makol, MD, Assistant Professor of Medicine, Divison of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota; Makol.ashima@mayo.edu.ORCID 0000-0002-8748-898X

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NCATS NIH HHS UL1 TR002377NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

objectiveFew studies have estimated the healthcare resource usage of patients with systemic sclerosis (SSc). The purpose of this study was to compare hospitalization among incident cases of SSc vs age- and sex-matched comparators.

methodsA retrospective, population-based cohort of patients with SSc in Olmsted County, Minnesota, from January 1, 1980, to December 31, 2016, was assembled. A 2:1 cohort of age- and sex-matched patients without SSc from the same population was randomly selected for comparison. All hospitalizations in the geographic area from January 1, 1987, to September 30, 2018, were obtained. Rates of hospitalization, lengths of stay, and readmissions were compared between groups.

resultsThere were 76 incident SSc cases and 155 non-SSc comparators (mean age 56 ± 16 yrs at diagnosis/index, 91% female) included. Rates of hospitalization among cases and comparators were 31.9 and 17.9 per 100 person-years, respectively (rate ratio [RR] 1.78, 95% CI 1.52-2.08). Hospitalization rates were higher in patients with SSc than comparators during the first 5 years after SSc diagnosis (RR 2.16, 95% CI 1.70-2.74). This difference decreased over time and was no longer significant at ≥ 15 years after SSc incidence/index. Lengths of stay (median [IQR] 4 [2-6] vs 3 [2-6],

conclusionPatients with SSc were hospitalized more frequently than comparators, indicating high inpatient care needs in this population. Hospitalization rates were highest during the first 5 years following SSc diagnosis.

Indexed as

HospitalizationScleroderma, SystemicAdultAgedCohort StudiesFemaleHumansIncidenceMaleMiddle AgedRetrospective Studiesfacilities and services utilizationhospitalizationsystemic sclerosis

Identifiers

PMID33191288
PMCPMC8121887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.