ArticleJournal of the International Neuropsychological Society : JINS2021
Impact of Cognitive Impairment and Dysarthria on Spoken Language in Multiple Sclerosis.
Article in Journal of the International Neuropsychological Society : JINS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Dissociable Effects of Dysarthria Etiology and Severity on the Minimally Detectable Change of Speech Intelligibility.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Post-swallowing voice-based aspiration screening in dysphagia using a deep learning approach: insights from audio segmentation.Scientific reports · 2026Article
- Exploring Methodological Decisions for Calculating the Minimally Detectable Change in Dysarthria: Reliability, Statistics, and Standard Error of Measurement.Journal of speech, language, and hearing research : JSLHR · 2025Article
- Adapting the Bogenhausen Dysarthria Scales (BoDyS) to Chilean Spanish Speakers: Face and Content Validation.Brain sciences · 2025Article
- Comparing manual and automated methods for calculating speaking rate in Parkinson's disease.JASA express letters · 2025Article
- From "invisible" to "audible": Features extracted during simple speech tasks classify patient-reported fatigue in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Article
- Measuring Quality of Life in the Speakers with Dysarthria: Reliability and Validity of the Persian Version of the Qol-Dys.Medical journal of the Islamic Republic of Iran · 2025Article
- Altered Functional Activation Is Associated With Speech Dysfunction in People With Multiple Sclerosis.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Review
- Volumetric and diffusion MRI abnormalities associated with dysarthria in multiple sclerosis.Brain communications · 2024Article
- Speech deficits in multiple sclerosis: a narrative review of the existing literature.European journal of medical research · 2023Review
- Singing and Speaking Ability in Parkinson's Disease and Spinocerebellar Ataxia.Journal of speech, language, and hearing research : JSLHR · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the impact of cognitive impairment on spoken language produced by speakers with multiple sclerosis (MS) with and without dysarthria.
methodSixty speakers comprised operationally defined groups. Speakers produced a spontaneous speech sample to obtain speech timing measures of speech rate, articulation rate, and silent pause frequency and duration. Twenty listeners judged the overall perceptual severity of the samples using a visual analog scale that ranged from no impairment to severe impairment (speech severity). A 2 × 2 factorial design examined main and interaction effects of dysarthria and cognitive impairment on speech timing measures and speech severity in individuals with MS. Each speaker group with MS was further compared to a healthy control group. Exploratory regression analyses examined relationships between cognitive and biopsychosocial variables and speech timing measures and perceptual judgments of speech severity, for speakers with MS.
resultsSpeech timing was significantly slower for speakers with dysarthria compared to speakers with MS without dysarthria. Silent pause durations also significantly differed for speakers with both dysarthria and cognitive impairment compared to MS speakers without either impairment. Significant interactions between dysarthria and cognitive factors revealed comorbid dysarthria and cognitive impairment contributed to slowed speech rates in MS, whereas dysarthria alone impacted perceptual judgments of speech severity. Speech severity was strongly related to pause duration.
conclusionsThe findings suggest the nature in which dysarthria and cognitive symptoms manifest in objective, acoustic measures of speech timing and perceptual judgments of severity is complex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.