ArticleNeurorehabilitation and neural repair2021
Predictive Value of Midsagittal Tissue Bridges on Functional Recovery After Spinal Cord Injury.
Article in Neurorehabilitation and neural repair, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain morphology changes after spinal cord injury: A voxel-based meta-analysis.Frontiers in neurology · 2022Pooled it
- Anti-Nogo-A NG101 treatment induces changes in spinal cord micro- and macrostructure following spinal cord injury.Nature communications · 2026Trial
- Brain Morphology in Subacute Spinal Cord Injury: Insights Into Functional Recovery Across Brain Networks.Brain and behavior · 2026Article
- Spinal cord lesion characteristics and early standing ability with and without epidural stimulation.Experimental brain research · 2026Article
- Linking neurological status to functional outcomes in spinal cord injury: a multi-class, task-specific approach.BMC biomedical engineering · 2026Article
- Cuneiform Nucleus Stimulation Can Assist Gait Training to Promote Locomotor Recovery in Individuals With Incomplete Tetraplegia.Annals of neurology · 2026Article
- Tissue bridges offer valuable insights into bladder and bowel outcomes in chronic cervical spinal cord injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Responsiveness to transcutaneous spinal stimulation for upper extremity recovery following spinal cord injury: A case series exploration of midsagittal tissue bridges.The journal of spinal cord medicine · 2025Article
- Lesion characteristics are associated with bowel, bladder, and overall independence following cervical spinal cord injury.The journal of spinal cord medicine · 2025Article
- Reliability of SCIseg Automated Measurement of Midsagittal Tissue Bridges in Spinal Cord Injuries Using an External Dataset.Topics in spinal cord injury rehabilitation · 2025Article
- SCIseg: Automatic Segmentation of Intramedullary Lesions in Spinal Cord Injury on T2-weighted MRI Scans.Radiology. Artificial intelligence · 2025Article
- Exploring the Landscape of Biomarkers in Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2025Review
- Mechanisms of Traumatic Spinal Cord Injury AIS Grade Conversion.Neurotrauma reports · 2025Review
- Extent of Traumatic Spinal Cord Injury Is Lesion Level Dependent and Predictive of Recovery: A Multicenter Neuroimaging Study.Journal of neurotrauma · 2024Observational
- Prognostic value of tissue bridges in cervical spinal cord injury: a longitudinal, multicentre, retrospective cohort study.The Lancet. Neurology · 2024Article
- SCIseg: Automatic Segmentation of T2-weighted Intramedullary Lesions in Spinal Cord Injury.medRxiv : the preprint server for health sciences · 2024Article
- Longitudinal motor system changes from acute to chronic spinal cord injury.European journal of neurology · 2024Article
- Recent developments and future avenues for human corticospinal neuroimaging.Frontiers in human neuroscience · 2024Review
- Electrical stimulation of the cuneiform nucleus enhances the effects of rehabilitative training on locomotor recovery after incomplete spinal cord injury.Frontiers in neuroscience · 2024Article
- The presence or absence of midsagittal tissue bridges and walking: a retrospective cohort study in spinal cord injury.Spinal cord · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe majority of patients with spinal cord injury (SCI) have anatomically incomplete lesions and present with preserved tissue bridges, yet their outcomes vary.
objectiveTo assess the predictive value of the anatomical location (ventral/dorsal) and width of preserved midsagittal tissue bridges for American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade conversion and SCI patient stratification into recovery-specific subgroups.
methodsThis retrospective longitudinal study includes 70 patients (56 men, age: 52.36 ± 18.58 years) with subacute (ie, 1 month) SCI (45 tetraplegics, 25 paraplegics), 1-month neuroimaging data, and 1-month and 12-month clinical data. One-month midsagittal T2-weighted scans were used to determine the location and width of tissue bridges. Their associations with functional outcomes were assessed using partial correlation and unbiased recursive partitioning conditional inference tree (URP-CTREE).
resultsFifty-seven (81.4%) of 70 patients had tissue bridges (2.53 ± 2.04 mm) at 1-month post-SCI. Larger ventral (
conclusionsMidsagittal tissue bridges add predictive value to baseline clinical measures for post-SCI recovery. Based on tissue bridges' width, patients can be classified into subgroups of clinical recovery profiles. Midsagittal tissue bridges provide means to optimize patient stratification in clinical trials.
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