Evidence map›Paper›PMID 33190592›Full record

ReviewAutophagy2021

Post translational modifications in tuberculosis: ubiquitination paradox.

Mohd Shariq, Neha Quadir, Javaid Ahmad Sheikh, Alok Kumar Singh, William R Bishai, Nasreen Z Ehtesham, Seyed E Hasnain

Open access · bronzeAbstract readReview
In one paragraph

Review in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Cell death pathways in response toInfection and immunity · 2025
    Review
  4. The Ubiquitination ofBiology · 2025
    Article
  5. Cysteine reactivity profiling identifies host regulators ofbioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Virulence · 2023
    Article
  11. Review
  12. Tuberculosis and Autoimmunity.Pathophysiology : the official journal of the International Society for Pathophysiology · 2022
    Review
  13. Review
  14. Review
  15. PGRS Domain of Rv0297 ofInternational journal of molecular sciences · 2021
    Article
  16. Frontiers in immunology · 2021
    Article
  17. Frontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mohd ShariqICMR-National Institute of Pathology, New Delhi, India.
Neha QuadirICMR-National Institute of Pathology, New Delhi, India.
Javaid Ahmad SheikhDepartment of Biotechnology, School of Chemical and Life Sciences, New Delhi, India.
Alok Kumar SinghJohns Hopkins School of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
William R BishaiJohns Hopkins School of Medicine, Center for Tuberculosis Research, Baltimore, MD, USA.
Nasreen Z EhteshamICMR-National Institute of Pathology, New Delhi, India.
Seyed E HasnainJH-Institute of Molecular Medicine, Jamia Hamdard, New Delhi, India.
Institute of Molecular Medicine · INJohns Hopkins University · USNational Institute of Pathology · INDepartment of Biotechnology · IN

Funding

PpiA, a multitasking mycobacterial virulence proteinR21AI143610 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BISHAI, WILLIAM RAMSES · 2019 to 2020
$450k
NIAID NIH HHS R21 AI143610
6 · The paper itself

Abstract

Innate immune signaling and xenophagy are crucial innate defense strategies exploited by the host to counteract intracellular pathogens with ubiquitination as a critical regulator of these processes. These pathogens, including

Indexed as

AutophagyHumansMacrophagesMycobacterium tuberculosisProtein Processing, Post-TranslationalTuberculosisUbiquitinationAutophagyMycobacterium tuberculosisubiquitinationvirulence effectorsxenophagy

Identifiers

PMID33190592
PMCPMC8032244
OpenAlexW3100519639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.