Evidence map›Paper›PMID 33190415›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

High prevalence of masked uncontrolled morning hypertension in elderly non-valvular atrial fibrillation patients: Home blood pressure substudy of the ANAFIE Registry.

Kazuomi Kario, Naoyuki Hasebe, Ken Okumura, Takeshi Yamashita, Masaharu Akao, Hirotsugu Atarashi, Takanori Ikeda, Yukihiro Koretsune, Wataru Shimizu, Hiroyuki Tsutsui and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. The roles of electrocardiography and self-screening in the early detection of atrial fibrillation in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Latest hypertension research to inform clinical practice in Asia.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  6. Article
  7. Clinical hypertension research in patients with atrial fibrillation: At last!Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 2 countries.

Kazuomi KarioDivision of Cardiovascular Medicine, Jichi Medical University, Tochigi, Japan.ORCID 0000-0002-8251-4480
Naoyuki HasebeDepartment of Cardiology, Nephrology, Pulmonology and Neurology, Asahikawa Medical University, Hokkaido, Japan.
Ken OkumuraDivision of Cardiology, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Takeshi YamashitaThe Cardiovascular Research Institute, Tokyo, Japan.
Masaharu AkaoDepartment of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Hirotsugu AtarashiMinami Hachioji Hospital, Tokyo, Japan.
Takanori IkedaDepartment of Cardiovascular Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Yukihiro KoretsuneNational Hospital Organization Osaka National Hospital, Osaka, Japan.
Wataru ShimizuDivision of Cardiology, Nippon Medical School, Tokyo, Japan.
Hiroyuki TsutsuiDepartment of Cardiovascular Medicine, Kyushu University, Fukuoka, Japan.
Kazunori ToyodaNational Cerebral and Cardiovascular Center, Suita, Japan.
Atsushi HirayamaOsaka Police Hospital, Osaka, Japan.
Masahiro YasakaDepartment of Cerebrovascular and Neurology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Takenori YamaguchiNational Cerebral and Cardiovascular Center, Suita, Japan.
Satoshi TeramukaiDepartment of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tetsuya KimuraMedical Science Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Jumpei KaburagiMedical Science Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Atsushi TakitaBiostatistics and Data Management Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Hiroshi InoueSaiseikai Toyama Hospital, Toyama, Japan.
Daiichi Sankyo (Germany) · DENational Cerebral and Cardiovascular Center · JPAsahikawa Medical University · JPCardiovascular Institute Hospital · JPJichi Medical University · JPKyoto Medical Center · JPKyoto Prefectural University of Medicine · JPKyushu University · JPNational Kyushu Medical Center · JPNippon Medical School · JPOsaka National Hospital · JPOsaka Police Hospital · JPSaiseikai Kumamoto Hospital · JPToho University · JPTokai University Hachioji Hospital · JPToyama University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the ANAFIE Registry home blood pressure subcohort, we evaluated 5204 patients aged ≥75 years with non-valvular atrial fibrillation (NVAF) to assess blood pressure (BP) control, prevalence of masked hypertension, and anticoagulant use. Mean clinic (C) and home (H) systolic/diastolic BP(SBP/DBP) was 128.5/71.3 and 127.7/72.6 mm Hg, respectively. Overall, 77.5% of patients had hypertension; of these, 27.7%, 13.4%, 23.4%, and 35.6% had well-controlled, white coat, masked, and sustained hypertension, respectively. Masked hypertension prevalence increased with diabetes, decreased renal function, age ≥80 years, current smoker status, and chronic obstructive pulmonary disease. By morning/evening average, 59.0% of patients had mean H-SBP ≥ 125 mm Hg; 48.9% had mean C-SBP ≥ 130 mm Hg. Early morning hypertension (morning H-SBP ≥ 125 mm Hg) was found in 65.9% of patients. Although 51.1% of patients had well-controlled C-SBP, 52.5% of these had uncontrolled morning H-SBP. In elderly NVAF patients, morning H-BP was poorly controlled, and masked uncontrolled morning hypertension remains significant.

Indexed as

Atrial FibrillationHypertensionMasked HypertensionAgedAged, 80 and overBlood PressureBlood Pressure Monitoring, AmbulatoryHumansPrevalenceRegistriesatrial fibrillationclinical blood pressureelderlyhome blood pressurehypertension

Identifiers

PMID33190415
PMCPMC8029869
OpenAlexW3099126472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.