ArticleInternational journal of laboratory hematology2021
Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19.
Article in International journal of laboratory hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Leukocyte cell population data predict 30-day mortality in community-acquired pneumonia: A multicenter prospective study.Biomolecules & biomedicine · 2026Observational
- Admission biomarkers and COVID-19 mortality: A retrospective study during Vietnam's pandemic peak.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Article
- Leukocyte cell population data as potential markers of COVID-19 disease characterization.Journal of medical biochemistry · 2023Article
- Biochemical and hematological findings and risk factors associated with kidney impairment in patients with COVID-19.Journal of medical biochemistry · 2023Article
- Dynamic alterations in white blood cell counts and SARS-CoV-2 shedding in saliva: an infection predictor parameter.Frontiers in medicine · 2023Article
- Are Lymphocytes and Eosinophils Associated with the COVID-19 Severity: A Large, Retrospective Study.Thoracic research and practice · 2023Article
- Monocyte distribution width adds prognostic value in detection of COVID-19 respiratory failure.International journal of laboratory hematology · 2022Article
- Longitudinal prediction of hospital-acquired acute kidney injury in COVID-19: a two-center study.Infection · 2022Article
- Hematological Findings among COVID-19 Patients Attending King Khalid Hospital at Najran, Kingdom of Saudi Arabia.BioMed research international · 2022Observational
- Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19.International journal of laboratory hematology · 2021Article
- Do Blood Eosinophils Predict in-Hospital Mortality or Severity of Disease in SARS-CoV-2 Infection? A Retrospective Multicenter Study.Microorganisms · 2021Article
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6 authors.
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Abstract
introductionEarly diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) abnormalities related to COVID-19 at disease onset.
methodsBaseline WBC counts and CPD data were analyzed in one hundred COVID-19 patients presenting to emergency department and subsequently discharged (n=49), admitted (n=51) or deceased (n=22), and in 47 healthy subjects.
resultsLymphopenia and eosinopenia were observed in all COVID-19 patients, with more intensity in the admitted and deceased groups, that also presented increased WBC and neutrophil counts. On CPD analysis, COVID-19 was associated with increased volume of neutrophils, lymphocytes, and monocytes, whereas conductivity was decreased for neutrophils and increased for lymphocytes. The ROC curve analysis showed good performance for lymphocyte counts in predicting COVID-19 diagnosis (AUC=0.858), for neutrophil counts in predicting admission for COVID-19 (AUC=0.744) and for monocytes volume in predicting COVID-19 diagnosis (AUC=0.837).
conclusionWBC counts and CPD parameters at disease onset in COVID-19 patients can improve diagnostic characterization and aid in the discrimination between severe and nonsevere presentations.
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