Evidence map›Paper›PMID 33190244›Full record

ArticleAlcoholism, clinical and experimental research2021

Cross-Sectional Analysis of Spatial Working Memory Development in Children with Histories of Heavy Prenatal Alcohol Exposure.

Eileen M Moore, Leila Glass, M Alejandra Infante, Claire D Coles, Julie A Kable, Kenneth L Jones, Edward P Riley, Sarah N Mattson, CIFASD

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Fetal Alcohol Spectrum Disorders.Current topics in behavioral neurosciences · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Eileen M MooreFrom the, Department of Psychology, (EMM, LG, MAI, EPR, SNM), Center for Behavioral Teratology, San Diego State University, San Diego, California.ORCID 0000-0002-9541-9503
Leila GlassFrom the, Department of Psychology, (EMM, LG, MAI, EPR, SNM), Center for Behavioral Teratology, San Diego State University, San Diego, California.
M Alejandra InfanteFrom the, Department of Psychology, (EMM, LG, MAI, EPR, SNM), Center for Behavioral Teratology, San Diego State University, San Diego, California.ORCID 0000-0003-2002-6286
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, (CDC), Emory University School of Medicine, Atlanta, Georgia.
Julie A KableDepartment of Pediatrics, (CDC, JAK), Emory University School of Medicine, Atlanta, Georgia.ORCID 0000-0001-5008-0887
Kenneth L JonesDepartment of Pediatrics, (KLJ), School of Medicine, University of California, San Diego, La Jolla, California.
Edward P RileyFrom the, Department of Psychology, (EMM, LG, MAI, EPR, SNM), Center for Behavioral Teratology, San Diego State University, San Diego, California.
Sarah N MattsonFrom the, Department of Psychology, (EMM, LG, MAI, EPR, SNM), Center for Behavioral Teratology, San Diego State University, San Diego, California.ORCID 0000-0001-8499-9605
CIFASD
San Diego State University · USEmory University · USUniversity of California, Los Angeles · USUniversity of California San Diego · US

Funding

Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
FASD in San Diego and Moscow (U01 Research Project)U01AA014834 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SARAH N MATTSON WELLER · 2003 to 2026
$12.4M
FASD Diagnostic Telemedicine ResourceU24AA014815 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lauren Gist, SARAH N MATTSON WELLER · 2003 to 2026
$5.6M
Brain Structure in Adults with FASD - L. Aguilar diversity supplementR01AA026994 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI RILEY, EDWARD P · 2018 to 2022
$1.8M
Utility of Olfactory Function Measures in Children with Prenatal Alcohol ExposureR00AA022661 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI MOORE, EILEEN MARIE · 2016 to 2018
$731k
Utility of Olfactory Function Measures in Children with Prenatal Alcohol ExposureK99AA022661 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI MOORE, EILEEN MARIE · 2014 to 2015
$189k
NIAAA NIH HHS K99 AA022661NIAAA NIH HHS K99/R00 AA022661NIAAA NIH HHS R00 AA022661NIAAA NIH HHS R01 AA026994NIAAA NIH HHS U01 AA014834NIAAA NIH HHS U24 AA014811NIAAA NIH HHS U24 AA014815
6 · The paper itself

Abstract

backgroundIn children with prenatal alcohol exposure, spatial working memory is affected and brain regions important for spatial working memory performance exhibit atypical neurodevelopment. We therefore hypothesized that children with prenatal alcohol exposure may also have atypical development of spatial working memory ability.

methodsWe examined the relation between spatial working memory and age using a cross-sectional developmental trajectory approach in youth with and without histories of heavy prenatal alcohol exposure. The Cambridge Neuropsychological Test Automated Battery Spatial Working Memory subtest was administered to children 5.0 to 16.9 years old.

resultsWhile the controls and children with prenatal alcohol exposure showed similar performance at younger ages, larger group differences were observed in older children. This effect was replicated in a separate sample.

conclusionsThe atypical brain development that has previously been reported in children with heavy prenatal alcohol exposure may have clinically relevant implications for cognitive development; however, longitudinal cognitive analyses are needed.

Indexed as

Child DevelopmentCognitionAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleFetal Alcohol Spectrum DisordersHumansMaleMemory, Short-TermSpatial MemoryCognitionDevelopmentFASDPrenatal AlcoholSpatial Working Memory

Identifiers

PMID33190244
PMCPMC7875477
OpenAlexW3103469179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.