Evidence map›Paper›PMID 33190176›Full record

ReviewCurrent oncology reports2020

Management of the Neck in Well-Differentiated Thyroid Cancer.

Panagiotis Asimakopoulos, Ashok R Shaha, Iain J Nixon, Jatin P Shah, Gregory W Randolph, Peter Angelos, Mark E Zafereo, Luiz P Kowalski, Dana M Hartl, Kerry D Olsen and 12 more

Open access · greenAbstract readReview
In one paragraph

Review in Current oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 10 countries.

Panagiotis AsimakopoulosHead and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. asimakopoulos@doctors.org.uk.ORCID 0000-0003-3366-7883
Ashok R ShahaHead and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Iain J NixonDepartment of Otorhinolaryngology Head and Neck Surgery, Edinburgh Royal Infirmary, Edinburgh, UK.
Jatin P ShahHead and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Gregory W RandolphDivision of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Peter AngelosDepartment of Surgery and MacLean Center for Clinical Medical Ethics, The University of Chicago, Chicago, IL, USA.
Mark E ZafereoHead and Neck Endocrine Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Luiz P KowalskiDepartment of Otorhinolaryngology-Head and Neck Surgery, A.C. Camargo Cancer Center, São Paulo, Brazil.
Dana M HartlDepartment of Otolaryngology-Head and Neck Surgery, Institut Gustave Roussy, Villejuif Cedex, France.
Kerry D OlsenDepartment of Otorhinolaryngology, Mayo Clinic, Rochester, MN, USA.
Juan P RodrigoDepartment of Otolaryngology, Hospital Universitario Central de Asturias-ISPA, Oviedo, Spain.
Vincent Vander PoortenDepartment of Otorhinolaryngology Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
Antti A MäkitieDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Alvaro SanabriaDepartment of Surgery, School of Medicine, Universidad de Antioquia/Hospital Universitario San Vicente Fundación, Medellín, Colombia.
Carlos SuárezInstituto de Investigación Sanitaria del Principado de Asturias and CIBERONC, ISCIII, University of Oviedo, Oviedo, Spain.
Miquel QuerDepartment of Otolaryngology-Head and Neck Surgery, University Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Francisco J CivantosDepartment of Otolaryngology-Head and Neck Surgery, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
K Thomas RobbinsDepartment of Otolaryngology Head and Neck Surgery, Southern Illinois University Medical School, Springfield, IL, USA.
Orlando Guntinas-LichiusENT Department, Jena University Hospital, Jena, Germany.
Marc HamoirDepartment of Head and Neck Surgery, UC Louvain, St Luc University Hospital and King Albert II Cancer Institute, Brussels, Belgium.
Alessandra RinaldoUniversity of Udine School of Medicine, Udine, Italy.
Alfio FerlitoInternational Head and Neck Scientific Group, Padua, Italy.
Memorial Sloan Kettering Cancer Center · USUniversidad de Oviedo · ESEdinburgh Royal Infirmary · GBHospital Universitario de San Vicente Fundación · COInstitut Gustave Roussy · FRJena University Hospital · DEKU Leuven · BEMassachusetts Eye and Ear Infirmary · USMayo Clinic · USSouthern Illinois University School of Medicine · USThe University of Texas MD Anderson Cancer Center · USUniversidade de São Paulo · BRUniversitat Autònoma de Barcelona · ESUniversity of Chicago Medical Center · USUniversity of Helsinki · FIUniversity of Miami · USUniversity of Udine · IT

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purpose of reviewIn this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. RECENT

findingsIncreased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

Indexed as

Neck DissectionHumansLymphatic MetastasisNeoplasm Recurrence, LocalThyroid NeoplasmsLymphatic metastasisNeck dissectionThyroid neoplasms

Identifiers

PMID33190176
PMCPMC8500240
OpenAlexW3103325051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.