ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2020
A cross-sectional study to evaluate depression and quality of life among patients with lymphoedema due to podoconiosis, lymphatic filariasis and leprosy.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence, assessment and correlates of mental health problems in neglected tropical diseases: a systematic review.International health · 2024Pooled it
- Family quality of life and associated factors among people with leprosy or podoconiosis/lymphatic filariasis with visible disabilities and their family members in Ethiopia: a baseline study for a randomized controlled trial.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026Trial
- Lower limb lymphoedema-related mental depression: A systematic review and meta-analysis of non-cancer-related studies.Global epidemiology · 2025Review
- Article
- Quality of Life, Disability, and Fungal Neglected Tropical Diseases.Current fungal infection reports · 2025Article
- Quality of life among leprosy patients: An analysis of associated factors.PLOS mental health · 2025Article
- Managing Lymphedema Induced by Lymphatic Filariasis: Implementing and Improving Care at the Individual and Programmatic Levels.The American journal of tropical medicine and hygiene · 2024Article
- Improving health behaviours and attitudes around podoconiosis in Northern Western Ethiopia: Implementation and intervention effectiveness.PLoS neglected tropical diseases · 2024Article
- 'The Lost Peace': Evidencing the Syndemic Relationship between Neglected Tropical Diseases and Mental Distress in Liberia.Tropical medicine and infectious disease · 2024Article
- Bearing the burden: Podoconiosis and mental health-A three-way comparative cross-sectional study in Rwanda.PLoS neglected tropical diseases · 2024Article
- Addressing the Syndemic Relationship between Lymphatic Filariasis and Mental Distress in Malawi: The Potential of Enhanced Self-Care.Tropical medicine and infectious disease · 2024Article
- Article
- The role of a community conversation intervention in reducing stigma related to lower limb lymphoedema in Northern Ethiopia.BMC health services research · 2024Article
- The relationship of kinesiophobia in patients with lymphedema: a case-control investigation.Frontiers in psychiatry · 2024Article
- Article
- Impact of basic psychological support on stigma and mental well-being of people with disabilities due to leprosy and lymphatic filariasis: a proof-of-concept study.International health · 2023Article
- Mental health conditions in people affected by filarial lymphoedema in Malawi: prevalence, associated risk factors and the impact of an enhanced self-care intervention.International health · 2023Article
- Stigma, depression and quality of life among people affected by neglected tropical diseases in Nepal.International health · 2023Article
- Examining the Relationships between the Incidence of Infectious Diseases and Mood Disorders: An Analysis of Data from the Global Burden of Disease Studies, 1990-2019.Diseases (Basel, Switzerland) · 2023Article
- Depressive symptoms and their severity in a sample with lymphedema: a case-control investigation.Frontiers in psychiatry · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundPodoconiosis, lymphatic filariasis (LF) and leprosy are neglected tropical diseases (NTDs) that cause lymphoedema. When left untreated, they lead to substantial disability. This study determined the quality of life (QOL) and depression associated with lymphoedema in patients with podoconiosis, LF and leprosy. The study was conducted in northwestern Ethiopia.
methodsThis baseline cross-sectional study, nested within an interventional, non-comparative, longitudinal study, included patients with lymphoedema. Depression and QOL were assessed using versions of the 9-item Patient Health Questionnaire and Dermatologic Life Quality Index (DLQI), respectively, that had been translated into Amharic and validated. Factors associated with depression and QOL were assessed using multivariate linear regression analysis.
resultsOf the 251 patients with lymphoedema included in the study, 119 (47.4%) had moderate to severe depression and overall QOL was poor (mean±standard deviation [SD] DLQI score: 11.4±4.2). Disability was significantly associated with depression (β=0.26 [95% confidence interval {CI} 0.19 to 0.33]). Currently receiving treatment (β=-3.05 [95% CI -5.25 to -0.85), disability (β=-0.08 [95% CI -0.15 to -0.01]) and social support (moderate support: β=-2.27 [95% CI -3.66 to -0.89] and strong support: β=-2.87 [95% CI -5.35 to -0.38]) were significantly associated with better QOL.
conclusionHigh levels of depression and low QOL were found among patients with lymphoedema due the three NTDs in Ethiopia.
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