Evidence map›Paper›PMID 33189502›Full record

ArticleAmerican journal of preventive medicine2021

Vaccine Hesitancy and Concerns About Vaccine Safety and Effectiveness in Shanghai, China.

Abram L Wagner, Zhuoying Huang, Jia Ren, Megan Laffoon, Mengdi Ji, Leah C Pinckney, Xiaodong Sun, Lisa A Prosser, Matthew L Boulton, Brian J Zikmund-Fisher

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abram L WagnerDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan. Electronic address: awag@umich.edu.
Zhuoying HuangDepartment of Immunization Program, Shanghai Municipal Centers for Disease Control and Prevention, Shanghai, China.
Jia RenDepartment of Immunization Program, Shanghai Municipal Centers for Disease Control and Prevention, Shanghai, China.
Megan LaffoonDepartment of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Mengdi JiDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Leah C PinckneyDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Xiaodong SunDepartment of Immunization Program, Shanghai Municipal Centers for Disease Control and Prevention, Shanghai, China.
Lisa A ProsserSusan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan.
Matthew L BoultonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; Department of Internal Medicine, Division of Infectious Disease, University of Michigan Medical School, Ann Arbor, Michigan.
Brian J Zikmund-FisherDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan; Department of Internal Medicine, Division of General Medicine, University of Michigan Medical School, Ann Arbor, Michigan.

Funding

Characterizing parental beliefs to support optimization of vaccine introductionK01AI137123 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WAGNER, ABRAM LUTHER · 2019 to 2023
$475k
NIAID NIH HHS K01 AI137123
6 · The paper itself

Abstract

introductionRapidly urbanizing communities in middle-income countries could be sources of vaccine hesitancy, and may create hot spots of low vaccination coverage. This study characterizes vaccine hesitancy in Shanghai and identifies disparities in vaccine safety and efficacy concerns by residency status-a marker for recent migration into the city.

methodsParents of children aged ≤18 years from immunization clinics in Shanghai were enrolled in summer 2019, with the data analyzed during winter 2019-2020. The paper questionnaire used the Parental Attitudes towards Childhood Vaccines scale, which included questions about vaccine safety and efficacy concerns. The primary independent variable was residency-whether an individual was a Shanghai local or a recent migrant (i.e., non-local). Linear regression models assessed the relationship between residency and vaccine safety and efficacy concerns.

resultsAmong 1,021 participants, 65.4% had local residency, and the remainder were urban non-locals (13.1%) or rural non-locals (21.5%). A majority of parents expressed concerns about vaccine side effects (73.8%), vaccine safety (63.9%), and vaccine effectiveness (52.4%). Compared with locals, rural non-locals were more concerned about vaccine side effects (β=0.26, 95% CI=0.07, 0.46), vaccine safety (β=0.42, 95% CI=0.19, 0.65), and vaccine effectiveness (β=0.37, 95% CI=0.16, 0.58).

conclusionsDifferences in vaccine hesitancy by residency could lead to geographical and sociodemographic disparities in vaccination coverage and outbreaks of vaccine-preventable disease. SUPPLEMENT INFORMATION: This article is part of a supplement entitled Global Vaccination Equity, which is sponsored by the Global Institute for Vaccine Equity at the University of Michigan School of Public Health.

Indexed as

VaccinesAdultChildChinaCitiesHealth Knowledge, Attitudes, PracticeHumansParentsPatient Acceptance of Health CareVaccinationVaccines

Identifiers

PMID33189502
PMCPMC7877188

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.